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Increases in regional brain volume across two native South American male populations.
Chaudhari, Nikhil N; Imms, Phoebe E; Chowdhury, Nahian F; Gatz, Margaret; Trumble, Benjamin C; Mack, Wendy J; Law, E Meng; Sutherland, M Linda; Sutherland, James D; Rowan, Christopher J; Wann, L Samuel; Allam, Adel H; Thompson, Randall C; Michalik, David E; Miyamoto, Michael; Lombardi, Guido; Cummings, Daniel K; Seabright, Edmond; Alami, Sarah; Garcia, Angela R; Rodriguez, Daniel E; Gutierrez, Raul Quispe; Copajira, Adrian J; Hooper, Paul L; Buetow, Kenneth H; Stieglitz, Jonathan; Gurven, Michael D; Thomas, Gregory S; Kaplan, Hillard S; Finch, Caleb E; Irimia, Andrei.
Afiliação
  • Chaudhari NN; Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
  • Imms PE; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
  • Chowdhury NF; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
  • Gatz M; Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
  • Trumble BC; Center for Economic and Social Research, Dana and David Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, USA.
  • Mack WJ; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA.
  • Law EM; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Sutherland ML; iBRAIN Research Laboratory, Departments of Neuroscience, Computer Systems and Electrical Engineering, Monash University, Melbourne, VIC, Australia.
  • Sutherland JD; Department of Radiology, The Alfred Health Hospital, Melbourne, VIC, Australia.
  • Rowan CJ; Department of Neurology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Wann LS; MemorialCare Health Systems, Fountain Valley, CA, USA.
  • Allam AH; MemorialCare Health Systems, Fountain Valley, CA, USA.
  • Thompson RC; Renown Institute for Heart and Vascular Health, Reno, NV, USA.
  • Michalik DE; School of Medicine, University of Nevada, Reno, NV, USA.
  • Miyamoto M; Division of Cardiology, University of New Mexico, Albuquerque, NM, USA.
  • Lombardi G; Department of Cardiology, School of Medicine, Al-Azhar University, Al Mikhaym Al Daem, Cairo, Egypt.
  • Cummings DK; Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City, MO, USA.
  • Seabright E; Department of Pediatrics, School of Medicine, University of California, Irvine, Orange, CA, USA.
  • Alami S; MemorialCare Miller Children's & Women's Hospital, Long Beach Medical Center, Long Beach, CA, USA.
  • Garcia AR; Division of Cardiology, Mission Heritage Medical Group, Providence Health, Mission Viejo, CA, USA.
  • Rodriguez DE; Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Gutierrez RQ; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA.
  • Copajira AJ; Economic Science Institute, Argyros School of Business and Economics, Chapman University, Orange, CA, USA.
  • Hooper PL; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA.
  • Buetow KH; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA.
  • Stieglitz J; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA.
  • Gurven MD; Institute of Biomedical Research, San Simon University, Cochabamba, Bolivia.
  • Thomas GS; Tsimane Health and Life History Project, San Borja, Beni, Bolivia.
  • Kaplan HS; Tsimane Health and Life History Project, San Borja, Beni, Bolivia.
  • Finch CE; Department of Anthropology, University of New Mexico, Albuquerque, NM, USA.
  • Irimia A; Center for Evolution & Medicine, School of Human Evolution and Social Change, School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Geroscience ; 46(5): 4563-4583, 2024 Oct.
Article em En | MEDLINE | ID: mdl-38683289
ABSTRACT
Industrialized environments, despite benefits such as higher levels of formal education and lower rates of infections, can also have pernicious impacts upon brain atrophy. Partly for this reason, comparing age-related brain volume trajectories between industrialized and non-industrialized populations can help to suggest lifestyle correlates of brain health. The Tsimane, indigenous to the Bolivian Amazon, derive their subsistence from foraging and horticulture and are physically active. The Moseten, a mixed-ethnicity farming population, are physically active but less than the Tsimane. Within both populations (N = 1024; age range = 46-83), we calculated regional brain volumes from computed tomography and compared their cross-sectional trends with age to those of UK Biobank (UKBB) participants (N = 19,973; same age range). Surprisingly among Tsimane and Moseten (T/M) males, some parietal and occipital structures mediating visuospatial abilities exhibit small but significant increases in regional volume with age. UKBB males exhibit a steeper negative trend of regional volume with age in frontal and temporal structures compared to T/M males. However, T/M females exhibit significantly steeper rates of brain volume decrease with age compared to UKBB females, particularly for some cerebro-cortical structures (e.g., left subparietal cortex). Across the three populations, observed trends exhibit no interhemispheric asymmetry. In conclusion, the age-related rate of regional brain volume change may differ by lifestyle and sex. The lack of brain volume reduction with age is not known to exist in other human population, highlighting the putative role of lifestyle in constraining regional brain atrophy and promoting elements of non-industrialized lifestyle like higher physical activity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Indígenas Sul-Americanos Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Bolivia Idioma: En Revista: Geroscience Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Indígenas Sul-Americanos Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Bolivia Idioma: En Revista: Geroscience Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça