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Metabolic imprinting in beef calves supplemented with creep feeding on performance, reproductive efficiency and metabolome profile.
Catussi, Bruna Lima Chechin; Ferreira, Jaqueline Rodrigues; Lo Turco, Edson Guimarães; Morgulis, Sérgio Carlos Franco; Baruselli, Pietro Sampaio.
Afiliação
  • Catussi BLC; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil. brunacatussi@usp.br.
  • Ferreira JR; Federal University of Mato grosso do Sul, Campo Grande, MS, Brazil.
  • Lo Turco EG; Ion Medicine Clinical Metabolomics, São Paulo, SP, Brazil.
  • Morgulis SCF; Minerthal Nutritional Products, São Paulo, SP, Brazil.
  • Baruselli PS; Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil.
Sci Rep ; 14(1): 9702, 2024 04 27.
Article em En | MEDLINE | ID: mdl-38678099
ABSTRACT
This experiment evaluated the influence of creep feeding supplementation on productive and reproductive performance and on serum metabolome profile in Nelore (Bos indicus) heifers. Female calves were assigned to treatments Creep (n = 190), with ad libitum access to a nutritional supplement from 70 to 220 days after birth, or Control (n = 140), without supplementation. After weaning (Day 220), both groups followed the same pasture and nutritional management. Body weight (BW) and backfat thickness (BFAT) were measured over time. Blood samples were collected at 220 and 360 days for LC-MS/MS targeted metabolomics. On day 408, during the synchronization timed artificial insemination (TAI) protocol, reproductive status (RS diameter of uterine horn and largest follicle, and presence of CL) was assessed. Creep feeding increased BW and BFAT at weaning, but no differences in BW, BFAT, or RS after weaning were observed. Nonetheless, the pregnancy per AI (P/AI) for 1st service was 28.9% higher in the Creep group. On day 220, 11 significant metabolites influenced five metabolic pathways Glucose-alanine cycle, alanine, glutathione, phenylalanine and tyrosine metabolism, and urea cycle. On day 360, 14 significant metabolites influenced eight metabolic pathways Malate-aspartate shuttle, arginine and proline metabolism, urea cycle, aspartate, beta-alanine, glutamate metabolism, ammonia recycling and citric acid cycle. In conclusion, creep feeding supplementation improved calf performance and induced metabolic changes at weaning and 360 days of age. Although heifers had similar productive performance and reproductive status, when submitted to TAI, those supplemented with creep feeding had greater P/AI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reprodução / Suplementos Nutricionais / Metaboloma / Ração Animal Limite: Animals / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reprodução / Suplementos Nutricionais / Metaboloma / Ração Animal Limite: Animals / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido