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Left ventricular concentric remodeling in COPD patients: A cross-sectional observational study.
Tais Leonardi, Naiara; da Silva Rocha Tomaz, Camila; Zavaglia Kabbach, Erika; Domingues Heubel, Alessandro; Souza Schafauser, Nathany; Mayumi de Oliveira Kawakami, Débora; Borghi-Silva, Audrey; Goi Roscani, Meliza; Castello-Simões, Viviane; Gonçalves Mendes, Renata.
Afiliação
  • Tais Leonardi N; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • da Silva Rocha Tomaz C; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Zavaglia Kabbach E; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Domingues Heubel A; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Souza Schafauser N; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Mayumi de Oliveira Kawakami D; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Borghi-Silva A; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Goi Roscani M; Department of Medicine, Federal University of Sao Carlos (UFSCar), Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Castello-Simões V; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil.
  • Gonçalves Mendes R; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil. Electronic address: renatamendes@ufscar.br.
Med Clin (Barc) ; 163(1): 8-13, 2024 07 12.
Article em En, Es | MEDLINE | ID: mdl-38614905
ABSTRACT

OBJECTIVE:

To investigate the association between left ventricular structure and disease severity in COPD patients.

METHODS:

Twenty-eight COPD patients were stratified according to the disease severity, using the BODE index, into Lower (n=17) and Higher (n=11) groups, composed of patients with lower severity (BODE <5) and higher severity (BODE ≥5), respectively. Left ventricle (LV) was assessed by 2D-echocardiography. BODE index was calculated using body mass index (BMI); forced expiratory volume in the first second (FEV1, %); modified Medical Research Council (mMRC) and distance walked during 6-minute walk test (6MWD).

RESULTS:

Patients in the Higher group showed lower oxygen arterial saturation (p=0.02), FEV1 (p<0.01) and 6MWD (p=0.02) and higher value of relative posterior wall thickness (RWT) compared to Lower group (p=0.02). There were significant associations between LV end-systolic diameter (LVESD) and BODE index (r=-0.38, p=0.04), LV end-diastolic diameter (LVEDD) and FEV1 (r=0.44, p=0.02), LVEDD and BMI (r=0.45, p=0.02), LVESD and BMI (r=0.54, p=0.003) and interventricular septal thickness and 6MWD (r=-0.39, p=0.04).

CONCLUSIONS:

More severe COPD patients, BODE score ≥5, may have higher RWT, featuring a possible higher concentric remodeling of LV in this group. Besides that, a greater disease severity may be related to LV chamber size reduction.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Remodelação Ventricular / Doença Pulmonar Obstrutiva Crônica Limite: Aged / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Remodelação Ventricular / Doença Pulmonar Obstrutiva Crônica Limite: Aged / Female / Humans / Male / Middle aged Idioma: En / Es Revista: Med Clin (Barc) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha