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Efficacy of a high concentration of nano silver fluoride in preventing caries: A randomized controlled trial.
de Lavôr, Juliane-Rolim; de Abreu, Rodolfo-Sinésio-Amador; Costa, Samylla-Glória-de Araújo; de Brito, Débora-Heloísa-Silva; Dos Santos, Thaysa-Gomes-Ferreira-Tenório; Almeida, Nathalia-Kelly-Veloso-de Lima; da Silva, Mabel-Cristina-Paiva-Machado; Júnior, Arnaldo-de França-Caldas; Heimer, Mônica-Vilela; Galembeck, André; Rosenblatt, Aronita.
Afiliação
  • de Lavôr JR; DDS, MSc, PhD student. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • de Abreu RS; DDS, MSc. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Costa SA; DDS, MSc student. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • de Brito DH; DDS, MSc, PhD student. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Dos Santos TG; DDS, MSc, PhD student. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Almeida NL; DDS, MSc student. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • da Silva MC; DDS, MSc, PhD. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Júnior AF; DDS, PhD, Professor. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Heimer MV; DDS, PhD, Professor. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
  • Galembeck A; DDS, PhD, Professor. Federal University of Pernambuco - Chemistry Department, Recife, Pernambuco, Brazil.
  • Rosenblatt A; DDS, PhD, Professor. University of Pernambuco, School of Dentistry - Department of Pediatric Dentistry, Recife, Pernambuco, Brazil.
J Clin Exp Dent ; 16(3): e263-e269, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38600926
ABSTRACT

Background:

To investigate the effectiveness of a novel agent containing Nano Silver Fluoride 1500 (NSF 1500) and chitosan to inactivate carious lesions in children. Material and

Methods:

The study included eighty children. While both groups had fluoride dentifrice applied to their teeth, only the experimental group received treatment with the NSF 1500-ppm solution. The first and sixth-month interval examinations were conducted by two calibrated dentists (k = 0.85).

Results:

The NSF 1500 group had 69.2% of their teeth with arrested decay, while the control group had 24.1%. The difference was statistically significant (p 0.001), with a preventive fraction of 59.4%. The number needed to treat (NNT) was approximately two. The NSF 1500 formulation was more effective than toothbrushing alone with fluoridated dentifrice in preventing dental caries.

Conclusions:

The effectiveness of NSF 1500 is determined by the size and depth of the dental cavity. Its ability to arrest caries lesions was comparable to previously tested products, NSF 400 and NSF 600. Key wordsPreventive dentistry, dental caries, nanoparticles.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Clin Exp Dent Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Clin Exp Dent Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha