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Key clinical predictors in the diagnosis of ovarian torsion in children.
Chen, Sai; Gao, Zhigang; Qian, Yunzhong; Chen, Qingjiang.
Afiliação
  • Chen S; Zhejiang University School of Medicine, The Children's Hospital, National Clinical Research Center for Child Health, Department of Pediatric General Surgery, Zhejiang Province, China.
  • Gao Z; Zhejiang University School of Medicine, The Children's Hospital, National Clinical Research Center for Child Health, Department of Pediatric General Surgery, Zhejiang Province, China.
  • Qian Y; Zhejiang University School of Medicine, The Children's Hospital, National Clinical Research Center for Child Health, Department of Pediatric General Surgery, Zhejiang Province, China.
  • Chen Q; Zhejiang University School of Medicine, The Children's Hospital, National Clinical Research Center for Child Health, Department of Pediatric General Surgery, Zhejiang Province, China. Electronic address: chensai829@zju.edu.cn.
J Pediatr (Rio J) ; 100(4): 399-405, 2024.
Article em En | MEDLINE | ID: mdl-38582497
ABSTRACT

OBJECTIVE:

Ovarian torsion (OT) represents a severe gynecological emergency in female pediatric patients, necessitating immediate surgical intervention to prevent ovarian ischemia and preserve fertility. Prompt diagnosis is, therefore, paramount. This retrospective study set out to assess the utility of combined clinical, ultrasound, and laboratory features in diagnosing OT.

METHODS:

The authors included 326 female pediatric patients aged under 14 years who underwent surgical confirmation of OT over a five-year period. Logistic regression analysis was employed to pinpoint factors linked with OT, and the authors compared clinical presentation, laboratory results, and ultrasound characteristics between patients with OT (OT group) and without OT (N-OT group). The authors conducted receiver operating characteristic (ROC) curve analysis to gauge the predictive capacity of the combined features.

RESULTS:

Among 326, OT was confirmed in 24.23 % (79 cases) of the patients. The OT group had a higher incidence of prenatal ovarian masses than the N-OT (22 cases versus 7 cases) (p < 0.0001). Similarly, the authors observed significant differences in the presence of lower abdominal pain, suspected torsion on transabdominal ultrasound, and a high neutrophil-lymphocyte ratio (NLR > 3) between the OT and non-OT groups (p ˂ 0.05). Furthermore, when these parameters were combined, the resulting area under the curve (AUC) was 0.868, demonstrating their potential utility in OT diagnosis.

CONCLUSION:

This study demonstrates a prediction model integrating clinical, laboratory, and ultrasound findings that can support the preoperative diagnosis of ovarian torsion, thereby enhancing diagnostic precision and improving patient management. Future prospective studies should concentrate on developing clinical predictive models for OT in pediatric patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ultrassonografia / Torção Ovariana Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant Idioma: En Revista: J Pediatr (Rio J) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ultrassonografia / Torção Ovariana Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant Idioma: En Revista: J Pediatr (Rio J) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Brasil