Risk of human leptospirosis in Colombia: spatiotemporal analysis and related hydroclimatic factors.
Trans R Soc Trop Med Hyg
; 118(9): 605-615, 2024 Sep 02.
Article
em En
| MEDLINE
| ID: mdl-38557833
ABSTRACT
BACKGROUND:
Leptospirosis is an endemic zoonosis in tropical areas that is mainly related to rural activities; nevertheless, human leptospirosis (HL) outbreaks differ among regions. In Colombia, HL notifications are mandatory. Our objective was to determine the spatiotemporal distribution of HL in Colombia during 2007-2018 and its relationship with the main hydroclimatic variables.METHODS:
We determined the estimated incidence and lethality of HL according to department and year. The Bayesian spatiotemporal analysis of an autoregressive model (STAR) model included HL cases and hydroclimatic factors (average temperature, rainfall and relative humidity) for quarterly periods.RESULTS:
During the study period, 10 586 HL cases were registered (estimated incidence 1.75 cases x 105) and 243 deaths by HL (lethality 2.3%). The STAR model found association of HL risk with temperature (RR6.80; 95% CI 3.57 to 12.48) and space. Quindío and three other Amazonian departments (Guainía, Guaviare and Putumayo) had a positive relationship with a significant number of HL cases, adjusted for quarterly precipitation and humidity.CONCLUSION:
Spatial analysis showed a high risk of HL in departments of the western Andean Colombian regions. By contrast, in the spatiotemporal model, a higher HL risk was associated with temperature and departments of the North Colombian Amazon regions and Quindío in the Colombian Andean region.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Teorema de Bayes
/
Análise Espaço-Temporal
/
Leptospirose
Limite:
Humans
País/Região como assunto:
America do sul
/
Colombia
Idioma:
En
Revista:
Trans R Soc Trop Med Hyg
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Reino Unido