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Two new glycosides from the root bark of Paeonia ostii.
Kong, Chuihao; Wang, Kaidi; Sun, Lei; Qin, Shihui; Wang, Renzhong; Xu, Fengqing.
Afiliação
  • Kong C; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, P. R. China.
  • Wang K; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, P. R. China.
  • Sun L; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, P. R. China.
  • Qin S; Zhejiang CONBA Pharmaceutical Co. LTD, Hangzhou, P. R. China.
  • Wang R; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, P. R. China.
  • Xu F; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, P. R. China.
Nat Prod Res ; : 1-7, 2024 Mar 03.
Article em En | MEDLINE | ID: mdl-38433399
ABSTRACT
Two new glycosides, ethyl-O-ß-D-furanosyl-(1→6)-O-ß-D-glucopyranoside (1) and (5-'')-galloyl-ethyl-O-ß-D-furanosyl-(1→6)-O-ß-D-glucopyranoside (2), together with eight known compounds (3-10) were obtained from the n-BuOH extraction of Paeonia ostii. Their structures were identified via the extensive spectroscopic analysis. Compounds 1, 3-10 exhibited the anti-inflammation activities, which inhibited the production of NO, TNF-α and IL-1ß in LPS-induced RAW264.7 cells with IC50 values ranging from 6.00 to 86.78 µΜ.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Prod Res Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Prod Res Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido