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Individual and joint effects of prenatal PM2.5 and maternal stress on child temperament.
McGuinn, Laura A; Klein, Daniel N; Gutiérrez-Avila, Iván; Keil, Alexander P; Tamayo-Ortiz, Marcela; Just, Allan; Coull, Brent; Torres-Calapiz, Mariana; Kloog, Itai; Téllez-Rojo, Martha Maria; Wright, Rosalind J; Wright, Robert O.
Afiliação
  • McGuinn LA; Institute for Population and Precision Health, University of Chicago, Chicago, IL, USA; Department of Family Medicine, University of Chicago, Chicago, IL, USA.
  • Klein DN; Department of Psychology, Stony Brook University, Stony Brook, NY, USA.
  • Gutiérrez-Avila I; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Keil AP; Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
  • Tamayo-Ortiz M; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA.
  • Just A; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Coull B; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Torres-Calapiz M; National Institute of Perinatology, Mexico City, Mexico.
  • Kloog I; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Geography and Environmental Development, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
  • Téllez-Rojo MM; Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
  • Wright RJ; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Wright RO; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Environ Res ; 249: 118432, 2024 May 15.
Article em En | MEDLINE | ID: mdl-38354885
ABSTRACT
Prenatal fine particulate matter (PM2.5) and maternal psychological functioning have been associated with child cognitive outcomes, though their independent and joint impacts on earlier behavioral outcomes remains less studied. We used data from 382 mother-child pairs from a prospective birth cohort in Mexico City. Temperament was measured at 24 months using the Carey Toddler Temperament Scale (TTS). Exploratory factor analysis (EFA) was used to update the factor structure of the TTS. During pregnancy, mothers completed the Crisis in Family Systems-Revised, Edinburgh Depression Scale, pregnancy-specific anxiety scale, and the Perceived Stress Scale. Pregnancy PM2.5 was assessed using estimates from a satellite-based exposure model. We assessed the association between prenatal maternal stress and PM2.5 on temperament, in both independent and joint models. Quantile g-computation was used to estimate the joint associations. Models were adjusted for maternal age, SES, education, child sex, and child age. In EFA, we identified three temperament factors related to effortful control, extraversion, and negative affect. Our main results showed that higher levels of PM2.5 and several of the maternal psychological functioning measures were related to both effortful control and negative affect in the child, both individually and as a mixture. For instance, a one quartile increase in the prenatal mixture was associated with higher negative affect scores in the child (0.34, 95% CI 0.16, 0.53). We observed modification of these associations by maternal SES, with associations seen only among lower SES participants for both effortful control (-0.45, 95% CI -0.70, -0.20) and negative affect outcomes (0.60, 95% CI 0.35, 0.85). Prenatal PM2.5 and maternal psychological functioning measures were associated with toddler temperament outcomes, providing evidence for impacts of chemical and non-chemical stressors on early child health.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Estresse Psicológico / Temperamento / Material Particulado Tipo de estudo: Prognostic_studies Limite: Adult / Child, preschool / Female / Humans / Male / Pregnancy País/Região como assunto: Mexico Idioma: En Revista: Environ Res Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Estresse Psicológico / Temperamento / Material Particulado Tipo de estudo: Prognostic_studies Limite: Adult / Child, preschool / Female / Humans / Male / Pregnancy País/Região como assunto: Mexico Idioma: En Revista: Environ Res Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda