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Antiulcer activity of Mauritia flexuosa L.f. (Arecaceae) pulp oil: An edible Amazonian species with functional properties.
Rodrigues, Maria de Fátima; da Silva, José Wellinton; de Lima, Jucielma Silva; Ramos, Bárbara de Azevedo; Paz, Silvania Tavares; Lomonaco, Diego; Zampieri, Davila; Ximenes, Rafael Matos.
Afiliação
  • Rodrigues MF; Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife 50740-525, Pernambuco, Brazil.
  • da Silva JW; Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife 50740-525, Pernambuco, Brazil.
  • de Lima JS; Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife 50740-525, Pernambuco, Brazil.
  • Ramos BA; Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife 50740-525, Pernambuco, Brazil.
  • Paz ST; Departamento de Patologia, Universidade Federal de Pernambuco, Recife 50670-910, Pernambuco, Brazil.
  • Lomonaco D; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza 60440-900, Ceará, Brazil.
  • Zampieri D; Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza 60440-900, Ceará, Brazil.
  • Ximenes RM; Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife 50740-525, Pernambuco, Brazil. Electronic address: rafael.ximenes@ufpe.br.
Fitoterapia ; 174: 105857, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38354821
ABSTRACT
Mauritia flexuosa, known as buriti in Brazil, is a widespread palm tree in Amazonia. It has many ethnobotanical uses, including food, oil, and medicine. The oil obtained from buriti's fruit pulp has high levels of monounsaturated fatty acids, carotenoids, and tocopherols, and is used in the food, cosmetic, and pharmaceutical industries for its antioxidant properties. Many biological activities have been reported for buriti oil, such as antioxidant, antimicrobial, chemopreventive, and immunomodulatory. Due to its high content of bioactive compounds, buriti oil is considered a functional ingredient with possible benefits in preventing oxidative stress and chronic diseases, particularly in the gastrointestinal tract. Peptic ulcer disease is a multifactorial disorder, involving lesions in the stomach and duodenum mucosa, which has a complex healing process. In this context, some nutrients and bioactive compounds help the maintenance of gastrointestinal mucosal integrity and function, such as carotenoids, tocopherols, and unsaturated fatty acids, which makes buriti oil an interesting candidate to be used in the prevention and management of gastrointestinal diseases. This study aimed to evaluate the gastroprotective and antiulcer effects of buriti oil and its possible mechanisms of action. Buriti oil reduced the ulcerative area and lipid peroxidation induced by ethanol. The gastroprotective activity of buriti oil partially depends on nitric oxide and sulfhydryl compounds. In acetic acid-induced gastric ulcers, buriti oil accelerated healing and stimulated the formation of new gastric glands. These results demonstrated the potential of buriti oil as a functional ingredient to promote health benefits in the gastrointestinal tract.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óleos de Plantas / Arecaceae / Antioxidantes Idioma: En Revista: Fitoterapia Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óleos de Plantas / Arecaceae / Antioxidantes Idioma: En Revista: Fitoterapia Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda