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Impact of influenza vaccination history in the clinical course of older adults hospitalized with COVID-19.
Hernández-Hernández, José G; Quintanilla-Flores, Dania L; González-Galván, Célica R; Nuzzolo-Shihadeh, Laura; Camacho-Ortiz, Adrián; Salinas-Martínez, Ricardo; Morales-Delgado, Rocío.
Afiliação
  • Hernández-Hernández JG; Servicio de Geriatría Clínica, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
  • Quintanilla-Flores DL; Departamento de Endocrinología, Hospital de Especialidades UMAE 25 del Instituto Mexicano del Seguro Social, IMSS, Monterrey, Nuevo León, Mexico.
  • González-Galván CR; Servicio de Geriatría Clínica, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
  • Nuzzolo-Shihadeh L; Servicio de Infectología, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
  • Camacho-Ortiz A; Servicio de Infectología, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
  • Salinas-Martínez R; Servicio de Geriatría Clínica, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
  • Morales-Delgado R; Servicio de Geriatría Clínica, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico. Electronic address: drarociomoralesdelgado@gmail.com.
Med Clin (Barc) ; 162(10): 477-482, 2024 05 31.
Article em En, Es | MEDLINE | ID: mdl-38342706
ABSTRACT
BACKGROUND AND

PURPOSE:

Some studies have shown that influenza vaccination is associated with a lower risk of SARS-CoV-2 infection; in patients with COVID-19 infection, admission to intensive care is reduced, with less need for mechanical ventilation, shorter hospital stays, and reduced mortality. This study aimed to determine if a history of annual influenza vaccination impacts the clinical course of SARS-CoV-2 infection during hospitalization.

METHODS:

This was an observational, prospective, cohort study of patients older than 65 admitted to the COVID-19 unit from January to June 2021. The history of influenza vaccination over the last 5 years was assessed in each patient during hospitalization. We measured the length of hospital stay, the need for admission to the intensive care unit (ICU), the patient's oxygen requirements, complications during hospitalization, and outcome (medical discharge or death). Patients with a history of vaccination against SARS-CoV-2 were not included.

RESULTS:

We analyzed 125 patients, 50.4% (n=63) with history of influenza vaccination and 49.6% (n=62) without a history of influenza vaccination. In-hospital mortality was 44.8%, higher in the unvaccinated (54.8%) population (p=0.008). ICU admission was 27% higher in vaccinated (35%) patients (p=0.05). Patients without a history of influenza vaccination had a higher prevalence of cardiac (8% vs. 5%, p=0.04) and renal complications (29% vs. 13%, p=0.02). Patients with a history of vaccination had a greater need for invasive mechanical ventilation (25.4%, p=0.02).

CONCLUSION:

In this study, a history of influenza vaccination in older adults with SARS-CoV-2 infection was related to lower in-hospital mortality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Mortalidade Hospitalar / Influenza Humana / COVID-19 / Hospitalização Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En / Es Revista: Med Clin (Barc) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Espanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra Influenza / Mortalidade Hospitalar / Influenza Humana / COVID-19 / Hospitalização Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male Idioma: En / Es Revista: Med Clin (Barc) Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Espanha