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Autistic individuals have worse oral status than neurotypical controls: a systematic review and meta-analysis of observational studies.
Uliana, Jaíne C; Del' Agnese, Catiusse C; Antoniazzi, Raquel P; Kantorski, Karla Z.
Afiliação
  • Uliana JC; Oral Science, School of Dentistry, Federal University of Santa Maria, Santa Maria, RS, Brazil.
  • Del' Agnese CC; Oral Science, School of Dentistry, Federal University of Santa Maria, Santa Maria, RS, Brazil.
  • Antoniazzi RP; Oral Science, School of Dentistry, Federal University of Santa Maria, Santa Maria, RS, Brazil.
  • Kantorski KZ; Oral Science, School of Dentistry, Federal University of Santa Maria, Santa Maria, RS, Brazil. kzkantorski@gmail.com.
Clin Oral Investig ; 28(2): 137, 2024 Feb 06.
Article em En | MEDLINE | ID: mdl-38321186
ABSTRACT

OBJECTIVE:

To compare dental caries, oral hygiene, periodontal status, bruxism, malocclusion, tooth loss, and salivary alterations between autistic and typical developing individuals. MATERIAL AND

METHODS:

Observational studies presenting clinical measures of oral outcomes between autism spectrum disorder (ASD) individuals and controls. EMBASE, LILACS, PubMed, PsycINFO, Scopus, Web of Science, Google Scholar, and ProQuest were searched up to June 26, 2023. Pairs of reviewers independently conducted study selection, data extraction, and assessments of methodological quality and certainty of evidence. Meta-analyses of standardized mean differences (SMD) and risk ratio (RR) were performed.

RESULTS:

A total of 47 studies comprising 6885 autistic individuals were included in the review. Autistic individuals had significantly higher severity of dental-caries experience in primary teeth (SMD 0.29, 95%CI 0.02, 0.56), of dental plaque presence (SMD 0.59, 95%CI 0.24, 0.94), and of gingivitis (SMD 0.45, 95%CI 0.02, 0.88). Autistic individuals showed higher probability of occurrence of gingivitis (RR 1.34, 95%CI 1.08, 1.66,), bruxism (RR 4.23, 95%CI 2.32, 7.74), overjet (RR 2.16, 95%CI 1.28, 3.64), overbite (RR 1.62, 95%CI 1.02, 2.59), crossbite (RR 1.48, 95%CI 1.02, 2.13), and openbite (RR 2.37, 95%CI 1.46, 3.85), when compared to neurotypical individuals. Most estimates showed a small effect size with very low certainty of evidence.

CONCLUSION:

Autistic individuals show worse oral health status than controls. CLINICAL RELEVANCE The findings reported herein can help to build health policies to better serve autistic individuals including prevention actions and access to specialized dental care.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudos Observacionais como Assunto Tipo de estudo: Observational_studies / Systematic_reviews Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Clin Oral Investig Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudos Observacionais como Assunto Tipo de estudo: Observational_studies / Systematic_reviews Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Clin Oral Investig Assunto da revista: ODONTOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha