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Basal characteristics of patients who responded to Ovarian Fragmentation for Follicular Activation (OFFA) or In Vitro Activation (IVA): a systematic review and meta-analysis.
Escarcega-Bordagaray, Jaime A; Torres-Martinez, Mauricio; Hinojosa-Gonzalez, David Eugenio; Ramírez-Díaz, Mónica; Fàbregues, Francesc; Carmona, Francisco.
Afiliação
  • Escarcega-Bordagaray JA; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, Mexico.
  • Torres-Martinez M; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, Mexico.
  • Hinojosa-Gonzalez DE; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, Mexico.
  • Ramírez-Díaz M; Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
  • Fàbregues F; Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey, Nuevo León, Mexico.
  • Carmona F; Department of Gynecology, Institut Clinic of Gynecology, Obstetrics and Neonatology, Hospital Clinic of Barcelona, Carrer de Villarroel, 170, 08036, Barcelona, Spain. fgasol@clinic.cat.
J Assist Reprod Genet ; 41(4): 989-998, 2024 Apr.
Article em En | MEDLINE | ID: mdl-38315420
ABSTRACT
A systematic review and meta-analysis were performed to identify if there is a subset of patients with POI who are more likely to show follicular growth after ovarian fragmentation for follicular activation (OFFA) or in vitro activation (IVA). Five studies met inclusion criteria for meta-analysis with a total of 164 patients. Forty-three patients showed follicle development (26.21%). Of those, the pregnancy rate was 35.58% (11/43) and the live birth rate was 20.93% (9/43). Our meta-analysis showed that age was not associated with follicle growth. However, lower baseline FSH, lower duration of amenorrhea/diagnosis, and presence of follicles remaining in biopsy were statistically significant for follicle development. Patients with basal characteristics mentioned before may have more chances to show follicle growth after OFFA or IVA. Taking into account that approximately 20% of patients with follicle growth had live birth, these results are very promising. Given the overall certainty of evidence, future studies are needed to confirm said results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indução da Ovulação / Fertilização in vitro / Taxa de Gravidez / Folículo Ovariano Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Pregnancy Idioma: En Revista: J Assist Reprod Genet Assunto da revista: GENETICA / MEDICINA REPRODUTIVA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Indução da Ovulação / Fertilização in vitro / Taxa de Gravidez / Folículo Ovariano Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Pregnancy Idioma: En Revista: J Assist Reprod Genet Assunto da revista: GENETICA / MEDICINA REPRODUTIVA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Holanda