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Therapeutic potential of psychedelics: History, advancements, and unexplored frontiers.
Maia, Juliana Marino; de Oliveira, Bruna Stefane Alves; Branco, Luiz G S; Soriano, Renato Nery.
Afiliação
  • Maia JM; Department of Medicine, Federal University of Juiz de Fora, Governador Valadares, MG 35032-620, Brazil.
  • de Oliveira BSA; Department of Medicine, Federal University of Juiz de Fora, Governador Valadares, MG 35032-620, Brazil.
  • Branco LGS; Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP 14040-904, Brazil; Department of Physiology, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP 14040-900, Brazil. Electronic address: branco@forp.usp.b
  • Soriano RN; Division of Physiology and Biophysics, Department of Basic Life Sciences, Federal University of Juiz de Fora, Governador Valadares, MG 35020-360, Brazil.
Article em En | MEDLINE | ID: mdl-38307161
ABSTRACT
Psychedelics (serotonergic hallucinogens) are psychoactive substances that can alter perception and mood, and affect cognitive functions. These substances activate 5-HT2A receptors and may exert therapeutic effects. Some of the disorders for which psychedelic-assisted therapy have been studied include depression, addiction, anxiety and post-traumatic stress disorder. Despite the increasing number of studies reporting clinical effectiveness, with fewer negative symptoms and, additionally, minimal side effects, questions remain to be explored in the field of psychedelic medicine. Although progress has been achieved, there is still little understanding of the relationship among human brain and the modulation induced by these drugs. The present article aimed to describe, review and highlight the most promising findings in the literature regarding the (putative) therapeutic effects of psychedelics.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Aditivo / Alucinógenos Limite: Humans Idioma: En Revista: Prog Neuropsychopharmacol Biol Psychiatry Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Aditivo / Alucinógenos Limite: Humans Idioma: En Revista: Prog Neuropsychopharmacol Biol Psychiatry Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido