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Modelling HIV/AIDS epidemiological complexity: A scoping review of Agent-Based Models and their application.
Anderle, Rodrigo Volmir; de Oliveira, Robson Bruniera; Rubio, Felipe Alves; Macinko, James; Dourado, Ines; Rasella, Davide.
Afiliação
  • Anderle RV; Institute of Collective Health, Federal University of Bahia (UFBA), Salvador, Brazil.
  • de Oliveira RB; Institute of Collective Health, Federal University of Bahia (UFBA), Salvador, Brazil.
  • Rubio FA; Institute of Collective Health, Federal University of Bahia (UFBA), Salvador, Brazil.
  • Macinko J; Departments of Health Policy and Management and Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, California, United States of America.
  • Dourado I; Institute of Collective Health, Federal University of Bahia (UFBA), Salvador, Brazil.
  • Rasella D; Institute of Collective Health, Federal University of Bahia (UFBA), Salvador, Brazil.
PLoS One ; 19(2): e0297247, 2024.
Article em En | MEDLINE | ID: mdl-38306355
ABSTRACT

OBJECTIVE:

To end the AIDS epidemic by 2030, despite the increasing poverty and inequalities, policies should be designed to deal with population heterogeneity and environmental changes. Bottom-up designs, such as the Agent-Based Model (ABM), can model these features, dealing with such complexity. HIV/AIDS has a complex dynamic of structural factors, risk behaviors, biomedical characteristics and interventions. All embedded in unequal, stigmatized and heterogeneous social structure. To understand how ABMs can model this complexity, we performed a scoping review of HIV applications, highlighting their potentialities.

METHODS:

We searched on PubMed, Web of Science, and Scopus repositories following the PRISMA extension for scoping reviews. Our inclusion criteria were HIV/AIDS studies with an ABM application. We identified the main articles using a local co-citation analysis and categorized the overall literature aims, (sub)populations, regions, and if the papers declared the use of ODD protocol and limitations.

RESULTS:

We found 154 articles. We identified eleven main papers, and discussed them using the overall category results. Most studies model Transmission Dynamics (37/154), about Men who have sex with Men (MSM) (41/154), or individuals living in the US or South Africa (84/154). Recent studies applied ABM to model PrEP interventions (17/154) and Racial Disparities (12/154). Only six papers declared the use of ODD Protocol (6/154), and 34/154 didn't mention the study limitations.

CONCLUSIONS:

While ABM is among the most sophisticated techniques available to model HIV/AIDS complexity. Their applications are still restricted to some realities. However, researchers are challenged to think about social structure due model characteristics, the inclusion of these features is still restricted to case-specific. Data and computational power availability can enhance this feature providing insightful results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Síndrome da Imunodeficiência Adquirida Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Síndrome da Imunodeficiência Adquirida Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos