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Two new sesquiterpene glycosides from the stems of Dendrobium henanense and their anti-inflammatory activity.
Wu, Si-Yu; Jie, Hui-Yang; Wu, De-Ling; Qin, Shi-Hui; Tang, Xu; Wang, Ren-Zhong; Xu, Feng-Qing.
Afiliação
  • Wu SY; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, People's Republic of China.
  • Jie HY; Taihe County Hospital of Traditional Chinese Medicine, Taihe, People's Republic of China.
  • Wu DL; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, People's Republic of China.
  • Qin SH; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, People's Republic of China.
  • Tang X; Anhui Province Key Laboratory of New Manufacturing Technology for Traditional Chinese Medicine Decoction Pieces, Hefei, People's Republic of China.
  • Wang RZ; Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, People's Republic of China.
  • Xu FQ; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, People's Republic of China.
Nat Prod Res ; : 1-6, 2024 Jan 16.
Article em En | MEDLINE | ID: mdl-38226496
ABSTRACT
Two new sesquiterpene glycosides, 8α,12,15ß-trihydroxycopacamphan-15-O-ß-D-glucopyranoside (1) and dendrobiumane C-11-O-ß-D-glucopyranoside (2), along with three known terpenoids (3-5) were isolated from the aerial stems of Dendrobium henanense. Their structures were elucidated based on NMR-spectroscopic and HR-MS analyses. All compounds could reduce the levels of NO, TNF-α and IL-1ß in LPS-induced RAW264.7 cells with IC50 values ranging from 10.37 to 34.55 µΜ.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Prod Res Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Prod Res Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido