Your browser doesn't support javascript.
loading
Clinical and Acoustic Alterations of Swallowing in Children Exposed to Zika Virus during Pregnancy in a Cohort in Amazonas, Brazil: A Case Series Study.
Rodrigues, Cristina de Souza; Souza, Raillon Keven Santos; Rocha Neto, Cosmo Vieira; Otani, Rodrigo Haruo; Batista, Daniel de Medeiros; Maia, Ana Karla Nelson de Oliveira; Filho, Kleber Pinheiro de Oliveira; Andrade, Thais Dourado de; Andrade Almeida, Emmilyn de; Maciel, Luiz Henrique Gonçalves; Castro, Lucíola de Fátima Albuquerque Almeida Peixoto; Abtibol-Bernardino, Marília Rosa; Baia-da-Silva, Djane Clarys; Benzecry, Silvana Gomes; Castilho, Marcia da Costa; Martínez-Espinosa, Flor Ernestina; Alecrim, Maria das Graças Costa; Santos, Rosane Sampaio; Botto-Menezes, Camila.
Afiliação
  • Rodrigues CS; Postgraduate Program in Tropical Medicine (PPGMT), University of Amazonas State (UEA), Manaus 69040-000, Brazil.
  • Souza RKS; Northern University Center (UniNorte), Manaus 69020-160, Brazil.
  • Rocha Neto CV; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Otani RH; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Batista DM; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Maia AKNO; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Filho KPO; Faculty of Pharmacy, University Nilton Lins, Manaus 69058-030, Brazil.
  • Andrade TD; Faculty of Pharmacy, University Nilton Lins, Manaus 69058-030, Brazil.
  • Andrade Almeida E; East Zone Children's Emergency Hospital, Manaus 69058-030, Brazil.
  • Maciel LHG; Postgraduate Program in Tropical Medicine (PPGMT), University of Amazonas State (UEA), Manaus 69040-000, Brazil.
  • Castro LFAAP; Postgraduate Program in Tropical Medicine (PPGMT), University of Amazonas State (UEA), Manaus 69040-000, Brazil.
  • Abtibol-Bernardino MR; Postgraduate Program in Tropical Medicine (PPGMT), University of Amazonas State (UEA), Manaus 69040-000, Brazil.
  • Baia-da-Silva DC; Department of Maternal and Child Health, Medical School, Federal University of Amazonas, Manaus 69020-160, Brazil.
  • Benzecry SG; Postgraduate Program in Tropical Medicine (PPGMT), University of Amazonas State (UEA), Manaus 69040-000, Brazil.
  • Castilho MDC; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Martínez-Espinosa FE; Faculty of Pharmacy, University Nilton Lins, Manaus 69058-030, Brazil.
  • Alecrim MDGC; Leônidas & Maria Deane Institute, Fiocruz Amazonia, Manaus 69057-070, Brazil.
  • Santos RS; School of Health Sciences, University of Amazonas State, Manaus 69065-001, Brazil.
  • Botto-Menezes C; Tropical Medicine Foundation Doutor Heitor Vieira Dourado (FMT-HVD), Manaus 69040-000, Brazil.
Viruses ; 15(12)2023 11 30.
Article em En | MEDLINE | ID: mdl-38140604
ABSTRACT
Oropharyngeal dysphagia (OD) is a swallowing disorder that involves difficulty in safely passing the food bolus from the oral cavity to the stomach. OD is a common problem in children with congenital Zika virus syndrome (CZS). In this case series, we describe the clinical and acoustic alterations of swallowing in children exposed to the Zika virus during pregnancy in a cohort from Amazonas, Brazil. From July 2019 to January 2020, 22 children were evaluated, 6 with microcephaly and 16 without microcephaly. The mean age among the participants was 35 months (±4.6 months). All children with microcephaly had alterations in oral motricity, mainly in the lips and cheeks. Other alterations were in vocal quality, hard palate, and soft palate. Half of the children with microcephaly showed changes in cervical auscultation during breast milk swallowing. In children without microcephaly, the most frequently observed alteration was in lip motricity, but alterations in auscultation during the swallowing of breast milk were not observed. Regarding swallowing food of a liquid and pasty consistency, the most frequent alterations were incomplete verbal closure, increased oral transit time, inadequacy in capturing the spoon, anterior labial leakage, and increased oral transit time. Although these events are more frequent in microcephalic children, they can also be seen in non-microcephalic children, which points to the need for an indistinct evaluation of children exposed in utero to ZIKV.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Zika virus / Infecção por Zika virus / Microcefalia / Malformações do Sistema Nervoso Limite: Child / Child, preschool / Female / Humans / Infant / Pregnancy País/Região como assunto: America do sul / Brasil Idioma: En Revista: Viruses Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Zika virus / Infecção por Zika virus / Microcefalia / Malformações do Sistema Nervoso Limite: Child / Child, preschool / Female / Humans / Infant / Pregnancy País/Região como assunto: America do sul / Brasil Idioma: En Revista: Viruses Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça