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Computer-aided autism diagnosis using visual attention models and eye-tracking: replication and improvement proposal.
Franco, Felipe O; Oliveira, Jessica S; Portolese, Joana; Sumiya, Fernando M; Silva, Andréia F; Machado-Lima, Ariane; Nunes, Fatima L S; Brentani, Helena.
Afiliação
  • Franco FO; Interunit PostGraduate Program on Bioinformatics, Institute of Mathematics and Statistics (IME), University of São Paulo (USP), 05508-090, São Paulo, SP, Brazil. franco@ime.usp.br.
  • Oliveira JS; Department of Psychiatry, University of São Paulo's School of Medicine (FMUSP), 05403-903, São Paulo-SP, Brazil. franco@ime.usp.br.
  • Portolese J; School of Arts, Sciences and Humanities (EACH), University of São Paulo (USP), 03828-000, São Paulo-SP, Brazil.
  • Sumiya FM; Department of Psychiatry, University of São Paulo's School of Medicine (FMUSP), 05403-903, São Paulo-SP, Brazil.
  • Silva AF; Department of Psychiatry, University of São Paulo's School of Medicine (FMUSP), 05403-903, São Paulo-SP, Brazil.
  • Machado-Lima A; Department of Psychiatry, University of São Paulo's School of Medicine (FMUSP), 05403-903, São Paulo-SP, Brazil.
  • Nunes FLS; School of Arts, Sciences and Humanities (EACH), University of São Paulo (USP), 03828-000, São Paulo-SP, Brazil.
  • Brentani H; School of Arts, Sciences and Humanities (EACH), University of São Paulo (USP), 03828-000, São Paulo-SP, Brazil.
BMC Med Inform Decis Mak ; 23(1): 285, 2023 12 14.
Article em En | MEDLINE | ID: mdl-38098001
ABSTRACT

BACKGROUND:

Autism Spectrum Disorder (ASD) diagnosis can be aided by approaches based on eye-tracking signals. Recently, the feasibility of building Visual Attention Models (VAMs) from features extracted from visual stimuli and their use for classifying cases and controls has been demonstrated using Neural Networks and Support Vector Machines. The present work has three

aims:

1) to evaluate whether the trained classifier from the previous study was generalist enough to classify new samples with a new stimulus; 2) to replicate the previously approach to train a new classifier with a new dataset; 3) to evaluate the performance of classifiers obtained by a new classification algorithm (Random Forest) using the previous and the current datasets.

METHODS:

The previously approach was replicated with a new stimulus and new sample, 44 from the Typical Development group and 33 from the ASD group. After the replication, Random Forest classifier was tested to substitute Neural Networks algorithm.

RESULTS:

The test with the trained classifier reached an AUC of 0.56, suggesting that the trained classifier requires retraining of the VAMs when changing the stimulus. The replication results reached an AUC of 0.71, indicating the potential of generalization of the approach for aiding ASD diagnosis, as long as the stimulus is similar to the originally proposed. The results achieved with Random Forest were superior to those achieved with the original approach, with an average AUC of 0.95 for the previous dataset and 0.74 for the new dataset.

CONCLUSION:

In summary, the results of the replication experiment were satisfactory, which suggests the robustness of the approach and the VAM-based approaches feasibility to aid in ASD diagnosis. The proposed method change improved the classification performance. Some limitations are discussed and additional studies are encouraged to test other conditions and scenarios.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Transtorno do Espectro Autista Limite: Humans Idioma: En Revista: BMC Med Inform Decis Mak Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Transtorno do Espectro Autista Limite: Humans Idioma: En Revista: BMC Med Inform Decis Mak Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido