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The efficient role of sodium alginate-based biodegradable dressings for skin wound healing application: a systematic review.
da Silva, Carina Maiara; Reis, Rui L; Correlo, Vitor M; Jahno, Vanusca Dalosto.
Afiliação
  • da Silva CM; Postgraduate Program in Materials Technology and Industrial Processes, Feevale University, Novo Hamburgo, Brazil.
  • Reis RL; 3B's Research Group (Biomaterials, Biodegradables, and Biomimetics), Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative medicine, Guimarães, Portugal.
  • Correlo VM; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal.
  • Jahno VD; 3B's Research Group (Biomaterials, Biodegradables, and Biomimetics), Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative medicine, Guimarães, Portugal.
J Biomater Sci Polym Ed ; 35(3): 397-414, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38096034
Injuries and damage to the skin can be caused by different reasons throughout human life. The use of sodium alginate in tissue dressing has been highly studied due to its intrinsic properties, including its degradation rate and biocompatibility, and the capacity of supporting tissue proliferation. The aim of this paper is to demonstrate evidences, through a systematic review method, to support the application of sodium alginate as a curative and as a potential accelerator in the healing of skin wounds. Four databases were used to develop this systematic review: Science Direct, PubMed, Scielo and Scopus. The time interval established for the search was from January 2016 to October 2023. After applying the exclusion and inclusion criteria, each selected article was evaluated and it was observed that the improvement of the mechanical properties of sodium alginate when correctly processed and crosslinked were evident. However, the increase of crosslinking affects as the wettability and the swelling of the biomaterials can cause limitations in mechanical properties and hidrophilic behavior. To achieve the ideal dressing, it is necessary to apply the optimal concentration of crosslinking and other substances, which can damage its hidrophilic characteristic. Thus, it was concluded that sodium alginate has every caracteristic desirable to develop an effective and safe dressing.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bandagens / Alginatos Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: J Biomater Sci Polym Ed Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bandagens / Alginatos Tipo de estudo: Systematic_reviews Limite: Humans Idioma: En Revista: J Biomater Sci Polym Ed Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido