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Prevalence of prediabetes in Mexico: a retrospective analysis of nationally representative surveys spanning 2016-2022.
Fermín-Martínez, Carlos A; Paz-Cabrera, César Daniel; Basile-Alvarez, Martín Roberto; Castro, Paulina Sánchez; Núñez-Luna, Alejandra; Perezalonso-Espinosa, Jerónimo; Ramírez-García, Daniel; Antonio-Villa, Neftali Eduardo; Vargas-Vázquez, Arsenio; Fernández-Chirino, Luisa; Carrillo-Herrera, Karime Berenice; Cabrera-Quintana, Leslie Alitzel; Rojas-Martínez, Rosalba; Seiglie, Jacqueline A; Bello-Chavolla, Omar Yaxmehen.
Afiliação
  • Fermín-Martínez CA; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Paz-Cabrera CD; MD/PhD (PECEM) Program, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Basile-Alvarez MR; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Castro PS; Especialidad en Medicina Preventiva, Instituto Nacional de Salud Pública, Mexico City, Mexico.
  • Núñez-Luna A; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Perezalonso-Espinosa J; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Ramírez-García D; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Antonio-Villa NE; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Vargas-Vázquez A; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Fernández-Chirino L; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Carrillo-Herrera KB; Especialidad en Medicina Preventiva, Instituto Nacional de Salud Pública, Mexico City, Mexico.
  • Cabrera-Quintana LA; Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
  • Rojas-Martínez R; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
  • Seiglie JA; Departmento de Endocrinología, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
  • Bello-Chavolla OY; Especialidad en Medicina Preventiva, Instituto Nacional de Salud Pública, Mexico City, Mexico.
Lancet Reg Health Am ; 28: 100640, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38076414
Background: Characterizing prediabetes phenotypes may be useful in guiding diabetes prevention efforts; however, heterogeneous criteria to define prediabetes have led to inconsistent prevalence estimates, particularly in low- and middle-income countries. Here, we estimated trends in prediabetes prevalence in Mexico across different prediabetes definitions and their association with prevalent cardiometabolic conditions. Methods: We conducted a serial cross-sectional analysis of National Health and Nutrition Surveys in Mexico (2016-2022), totalling 22 081 Mexican adults. After excluding individuals with diagnosed or undiagnosed diabetes, we defined prediabetes using ADA (impaired fasting glucose [IFG] 100-125 mg/dL and/or HbA1c 5.7-6.4%), WHO (IFG 110-125 mg/dL), and IEC criteria (HbA1c 6.0-6.4%). Prevalence trends of prediabetes over time were evaluated using weighted Poisson regression and its association with prevalent cardiometabolic conditions with weighted logistic regression. Findings: The prevalence of prediabetes (either IFG or high HbA1c [ADA]) in Mexico was 20.9% in 2022. Despite an overall downward trend in prediabetes (RR 0.973, 95% CI 0.957-0.988), this was primarily driven by decreases in prediabetes by ADA-IFG (RR 0.898, 95% CI 0.880-0.917) and WHO-IFG criteria (RR 0.919, 95% CI 0.886-0.953), while prediabetes by ADA-HbA1c (RR 1.055, 95% CI 1.033-1.077) and IEC-HbA1C criteria (RR 1.085, 95% CI 1.045-1.126) increased over time. Prediabetes prevalence increased over time in adults >40 years, with central obesity, self-identified as indigenous or living in urban areas. For all definitions, prediabetes was associated with an increased risk of cardiometabolic conditions. Interpretation: Prediabetes rates in Mexico from 2016 to 2022 varied based on defining criteria but consistently increased for HbA1c-based definitions and high-risk subgroups. Funding: This research was supported by Instituto Nacional de Geriatría in Mexico. JAS was supported by NIH/NIDDK Grant# K23DK135798.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Mexico Idioma: En Revista: Lancet Reg Health Am Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Mexico Idioma: En Revista: Lancet Reg Health Am Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido