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Efficacy and Safety of Celiac Plexus Neurolysis in the Treatment of Chronic Pain Secondary to Oncological Pathology of the Upper Hemiabdomen: A Systematic Review and Meta-Analysis.
Pacheco-Feijoó, Gloria Melissa; Amado-Tineo, Jose Percy; Plancarte-Sánchez, Ricardo; Valdivia, Carlos Contreras; López-Millán, José M.
Afiliação
  • Pacheco-Feijoó GM; Department of Anesthesiology, Edgardo Rebagliati Martins National Hospital, Lima, Peru.
  • Amado-Tineo JP; Department of Medicine, School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.
  • Plancarte-Sánchez R; Clínica Del Dolor, Instituto Nacional de Cancerología, Mexico City, Mexico.
  • Valdivia CC; Department of Anesthesiology, Edgardo Rebagliati Martins National Hospital, Lima, Peru.
  • López-Millán JM; Department of Anesthesiology-Critical Care and Pain Medicine, Virgen Macarena University Hospital, Seville, Spain.
Indian J Palliat Care ; 29(4): 394-406, 2023.
Article em En | MEDLINE | ID: mdl-38058484
Objectives: The management of chronic pain among patients with abdominal cancer is complex; against that, the neurolysis of the celiac plexus (CPN) is the best technique at the moment to determine the efficacy and safety in the treatment of chronic pain secondary to oncological pathology of the upper abdomen. Material and Methods: This was a systematic review of controlled clinical trials between 2000 and 2021, in the sources MEDLINE/PubMed, Cochrane, Scopus, Web of Science, and Google Scholar. Three independent evaluators analysed the results of the bibliographical research. The quality of the studies was assessed with the Jadad scale and the mean difference (95% confidence interval) and heterogeneity of the studies (I2) were calculated with Review Manager 5.3. Results: Seven hundred and forty-four publications were identified, including 13 studies in the qualitative synthesis and three studies in the quantitative synthesis. No difference was found in the decrease in pain intensity between 1 and 12 weeks after the intervention, comparing the experimental group with the control (P > 0.05). The adverse effects related to neurolysis were not serious and transitory, mentioning the most frequent adverse effects and reporting a percentage between 21% and 67% (with 17% for echoendoscopic neurolysis and 49% for percutaneous neurolysis). Conclusion: Celiac plexus neurolysis for the treatment of severe chronic pain secondary to oncological pathology in the upper hemiabdomen produces similar pain relief as conventional pharmacological analgesic treatment. It is a safe analgesic technique since the complications are mild and transitory.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Systematic_reviews Idioma: En Revista: Indian J Palliat Care Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Systematic_reviews Idioma: En Revista: Indian J Palliat Care Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Peru País de publicação: Estados Unidos