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Silk fibroin-derived electrospun materials for biomedical applications: A review.
Dos Santos, Francisco Vieira; Siqueira, Renato Luiz; de Morais Ramos, Lucas; Yoshioka, Sérgio Akinobu; Branciforti, Márcia Cristina; Correa, Daniel Souza.
Afiliação
  • Dos Santos FV; Nanotechnology National Laboratory for Agriculture, Embrapa Instrumentação, 13560-970 São Carlos, SP, Brazil; Materials Engineering Department, São Carlos School of Engineering, University of São Paulo, 13563-120 São Carlos, SP, Brazil.
  • Siqueira RL; Materials Engineering Department, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil.
  • de Morais Ramos L; São Carlos Institute of Physics, University of São Paulo, 13560-970 São Carlos, SP, Brazil.
  • Yoshioka SA; Laboratory of Biochemistry and Biomaterials, São Carlos Institute of Chemistry, University of São Paulo, 13560-970 São Carlos, SP, Brazil.
  • Branciforti MC; Materials Engineering Department, São Carlos School of Engineering, University of São Paulo, 13563-120 São Carlos, SP, Brazil.
  • Correa DS; Nanotechnology National Laboratory for Agriculture, Embrapa Instrumentação, 13560-970 São Carlos, SP, Brazil; Materials Engineering Department, São Carlos School of Engineering, University of São Paulo, 13563-120 São Carlos, SP, Brazil. Electronic address: daniel.correa@embrapa.br.
Int J Biol Macromol ; 254(Pt 2): 127641, 2024 Jan.
Article em En | MEDLINE | ID: mdl-37913875
Electrospinning is a versatile technique for fabricating polymeric fibers with diameters ranging from micro- to nanoscale, exhibiting multiple morphologies and arrangements. By combining silk fibroin (SF) with synthetic and/or natural polymers, electrospun materials with outstanding biological, chemical, electrical, physical, mechanical, and optical properties can be achieved, fulfilling the evolving biomedical demands. This review highlights the remarkable versatility of SF-derived electrospun materials, specifically focusing on their application in tissue regeneration (including cartilage, cornea, nerves, blood vessels, bones, and skin), disease treatment (such as cancer and diabetes), and the development of controlled drug delivery systems. Additionally, we explore the potential future trends in utilizing these nanofibrous materials for creating intelligent biomaterials, incorporating biosensors and wearable sensors for monitoring human health, and also discuss the bottlenecks for its widespread use. This comprehensive overview illuminates the significant impact and exciting prospects of SF-derived electrospun materials in advancing biomedical research and applications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanofibras / Fibroínas Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanofibras / Fibroínas Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda