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Biochemical Changes in Cardiopulmonary Bypass in Cardiac Surgery: New Insights.
Ferreira, Luan Oliveira; Vasconcelos, Victoria Winkler; Lima, Janielle de Sousa; Vieira Neto, Jaime Rodrigues; da Costa, Giovana Escribano; Esteves, Jordana de Castro; de Sousa, Sallatiel Cabral; Moura, Jonathan Almeida; Santos, Felipe Ruda Silva; Leitão Filho, João Monteiro; Protásio, Matheus Ramos; Araújo, Pollyana Sousa; Lemos, Cláudio José da Silva; Resende, Karina Dias; Lopes, Dielly Catrina Favacho.
Afiliação
  • Ferreira LO; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Vasconcelos VW; Laboratory of Experimental Neuropathology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Lima JS; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Vieira Neto JR; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • da Costa GE; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Esteves JC; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • de Sousa SC; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Moura JA; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Santos FRS; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Leitão Filho JM; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Protásio MR; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
  • Araújo PS; Hospital Israelita Albert Einstein-HIAE, São Paulo 05652-900, Brazil.
  • Lemos CJDS; Department of Cardiovascular Anesthesiology, Hospital Clínicas Gaspar Vianna, Belém 66083-106, Brazil.
  • Resende KD; Department of Cardiovascular Anesthesiology, Hospital Clínicas Gaspar Vianna, Belém 66083-106, Brazil.
  • Lopes DCF; Residency Program in Anesthesiology, João de Barros Barreto University Hospital, Federal University of Pará, Belém 66073-000, Brazil.
J Pers Med ; 13(10)2023 Oct 18.
Article em En | MEDLINE | ID: mdl-37888117
Patients undergoing coronary revascularization with extracorporeal circulation or cardiopulmonary bypass (CPB) may develop several biochemical changes in the microcirculation that lead to a systemic inflammatory response. Surgical incision, post-CPB reperfusion injury and blood contact with non-endothelial membranes can activate inflammatory signaling pathways that lead to the production and activation of inflammatory cells, with cytokine production and oxidative stress. This inflammatory storm can cause damage to vital organs, especially the heart, and thus lead to complications in the postoperative period. In addition to the organic pathophysiology during and after the period of exposure to extracorporeal circulation, this review addresses new perspectives for intraoperative treatment and management that may lead to a reduction in this inflammatory storm and thereby improve the prognosis and possibly reduce the mortality of these patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pers Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Pers Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça