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Postbiotics in the medical field under the perspective of the ISAPP definition: scientific, regulatory, and marketing considerations.
Vinderola, Gabriel; Druart, Céline; Gosálbez, Luis; Salminen, Seppo; Vinot, Nina; Lebeer, Sarah.
Afiliação
  • Vinderola G; Instituto de Lactología Industrial (CONICET-UNL), Faculty of Chemical Engineering, National University of Litoral, Santa Fe, Argentina.
  • Druart C; Pharmabiotic Research Institute, Narbonne, France.
  • Gosálbez L; Sandwalk Bioventures, Madrid, Spain.
  • Salminen S; Functional Foods Forum, Faculty of Medicine, University of Turku, Turku, Finland.
  • Vinot N; TargEDys, Longjumeau, France.
  • Lebeer S; Department of Bioscience Engineering, Research Group Environmental Ecology and Applied Microbiology, University of Antwerp, Antwerp, Belgium.
Front Pharmacol ; 14: 1239745, 2023.
Article em En | MEDLINE | ID: mdl-37745060
Diverse terms have been used in the literature to refer to the health benefits obtained from the administration of non-viable microorganisms or their cell fragments and metabolites. In an effort to provide continuity to this emerging field, the International Scientific Association of Probiotics and Prebiotics (ISAPP) convened a panel of experts to consider this category of substances and adopted the term postbiotic, which they defined as a "preparation of inanimate microorganisms and/or their components that confers a health benefit on the host." This definition does not stipulate any specific health benefit, finished product, target population or regulatory status. In this perspective article, we focused on postbiotics developed for pharmaceutical uses, including medicinal products and medical devices. We address how this field is regulated for products based on inanimate microorganisms, marketing considerations and existing examples of postbiotics products developed as cosmetics for the skin, for vaginal health, and as orally consumed products. We focus on the European Union for regulatory aspects, but also give examples from other geographical areas.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Argentina País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Argentina País de publicação: Suíça