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Use of Intralesional and Perilesional Human Recombinant Epidermal Growth Factor (hrEGF) in the Local Treatment of Venous Ulcer - Review Article - Expert Recommendation.
Cacua Sanchez, Maria Teresa; Vargas Abello, Lina M; Orrego, Álvaro; Ortiz, Paola; Segura, Héctor; Berrio Caicedo, Jhon Jairo; Zuluaga, Luz Marina; Ordoñez, José; Fernández Montequin, José Ignacio; Ulloa, Jorge.
Afiliação
  • Cacua Sanchez MT; Ambulatory Surgery Center, Kennedy Hospital, Vascular Laboratory SURA, Bogotá, Colombia.
  • Vargas Abello LM; Lumina Vein & Aesthetic Institute, Windermere, FL, USA.
  • Orrego Á; Laser & Veins Clinic, Viña del Mar, Chile.
  • Ortiz P; Uruguay Vein Center, Universidad de la República Oriental de Uruguay, Montevideo, Uruguay.
  • Segura H; Vascular and Endovascular Surgery Department, Hospital Español, Mexico City, Mexico.
  • Berrio Caicedo JJ; Universidad Del Valle, San José de Buga Hospital Foundation, Buga, Colombia.
  • Zuluaga LM; San Juan de Dios Hospital, Cartago Valle, Colombia.
  • Ordoñez J; Department of Vascular Surgery, Fundación Santa Fe, Bogotá, Colombia.
  • Fernández Montequin JI; National Institute of Angiology and Vascular Surgery, Havana, Cuba.
  • Ulloa J; Department of Vascular Surgery, Fundación Santa Fe de Bogotá, Universidad de los Andes, Bogota, Colombia.
Vasc Health Risk Manag ; 19: 595-603, 2023.
Article em En | MEDLINE | ID: mdl-37701155
Venous Ulcers (VU) represent 60-80% of all leg ulcers and are the final stage of the disease secondary to venous hypertension or valve insufficiency. Conventional treatment that focuses on its etiological factors continues to be the gold standard; however, 30% of ulcers do not heal with this treatment; thus, it has been seen that the use of growth factor can be used as an adjuvant for this pathology. A literature review was carried out to evaluate the evidence from systematic reviews, meta-analyses, case studies, and quantitative studies that respond to the objective of this analysis review in the different databases with specific inclusion criteria with publications between 2002 and 2022, initially finding the topical application of the factor and later, more recently, the intralesional and perilesional application, the latter being an alternative treatment for this type of pathology and generating some recommendations for using the Factor.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Úlcera Varicosa / Hipertensão / Úlcera da Perna Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Revista: Vasc Health Risk Manag Assunto da revista: ANGIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Nova Zelândia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Úlcera Varicosa / Hipertensão / Úlcera da Perna Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Revista: Vasc Health Risk Manag Assunto da revista: ANGIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Nova Zelândia