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Prevalence of SARS-CoV-2 Variants and Disease Outcome of COVID-19 Patients in the Amazonas Region of Peru.
Campos, Christian J; Pajuelo-Reyes, Cecilia; Rojas, Luis M; De La Cruz-Vargas, Jhony A; Tejedo, Juan R; Tapia-Limonchi, Rafael; Tsukayama, Pablo; Chenet, Stella M.
Afiliação
  • Campos CJ; Laboratorio Referencial de Salud de Chachapoyas, Dirección Regional de Salud Amazonas, Chachapoyas, Perú.
  • Pajuelo-Reyes C; Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas, Perú.
  • Rojas LM; Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas, Perú.
  • De La Cruz-Vargas JA; Laboratorio Referencial de Salud de Chachapoyas, Dirección Regional de Salud Amazonas, Chachapoyas, Perú.
  • Tejedo JR; Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas, Perú.
  • Tapia-Limonchi R; Instituto de Investigaciones en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, Perú.
  • Tsukayama P; Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas, Perú.
  • Chenet SM; Departamento de Biología Molecular e Ingeniería Bioquímica, Universidad Pablo de Olavide, Seville, Spain.
Am J Trop Med Hyg ; 109(3): 523-526, 2023 09 06.
Article em En | MEDLINE | ID: mdl-37524331
Peru was severely affected by COVID-19 with a fatality rate that reached up to 6%. In this study, the relationship between SARS-CoV-2 variants and COVID-19 disease outcome in Amazonas, a region of northeastern Peru, was evaluated. The variants were determined by genomic sequencing, and clinical-epidemiological data were collected from 590 patients between April 2021 and February 2022. There was no association between mortality and hospitalization with any of the variants, but we did find that Omicron is more likely to infect vaccinated and nonvaccinated people. A significant association was also found between unvaccinated patients and hospitalization. Interestingly, in the indigenous population, there were fewer hospitalizations than in the general population. In conclusion, SARS-CoV-2 variants were not associated with the disease outcome in the Amazonas region, and indigenous population were found to be less vulnerable to severe COVID-19 illness.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Peru Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Humans País/Região como assunto: America do sul / Peru Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos