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A prospective study of visceral leishmaniasis in an endemic area of Brazil.
J Infect Dis ; 154(4): 639-49, 1986 Oct.
Article em En | MEDLINE | ID: mdl-3745974
The epidemiology, clinical patterns, and risk factors for visceral leishmaniasis were prospectively studied in an endemic area of Brazil. The prevalence of disease was 3.1% for children less than 15 years of age, and the annual incidence was 4.3 cases per 1,000 children. The number of children with disease fluctuated yearly and seasonally, and distribution of the disease varied within the endemic area. Risk factors included young age (median, three years) and malnutrition before the onset of disease. Intestinal parasitism, recent migration into the area, and house location within the area did not influence the progression of infection to disease. Serological testing indicated that 7.5% of children were infected with Leishmania each year and that the ratio of disease to infection was 1:18.5 for the whole area and 1:6.5 for the section with the highest prevalence of disease. Early diagnosis and therapy altered clinical patterns of the disease.
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Visceral Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Infect Dis Ano de publicação: 1986 Tipo de documento: Article País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leishmaniose Visceral Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: J Infect Dis Ano de publicação: 1986 Tipo de documento: Article País de publicação: Estados Unidos