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Mortality, health-related quality of life, and depression symptoms in younger and older men and women undergoing hemodialysis.
da Silva, Fernanda Albuquerque; Silva Martins, Marcia Tereza; Gutiérrez-Peredo, Gabriel Brayan; Kraychete, Angiolina Campos; Penalva, Carolina Cartaxo; Lopes, Marcelo Barreto; Matos, Cacia Mendes; Lopes, Antonio Alberto.
Afiliação
  • da Silva FA; NEPHRON Clinic, Salvador, BA, Brazil.
  • Silva Martins MT; Postgraduate Program in Medicine and Health, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
  • Gutiérrez-Peredo GB; Postgraduate Program in Medicine and Health, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
  • Kraychete AC; Clinic of Renal Disease and Hypertension (CLINIRIM), Salvador, BA, Brazil.
  • Penalva CC; Postgraduate Program in Medicine and Health, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
  • Lopes MB; Postgraduate Program in Medicine and Health, Federal University of Bahia (UFBA), Salvador, BA, Brazil.
  • Matos CM; Institute of Nephrology and Dialysis (INED), Salvador, BA, Brazil.
  • Lopes AA; NEPHRON Clinic, Salvador, BA, Brazil.
Int J Artif Organs ; 46(8-9): 492-497, 2023 Sep.
Article em En | MEDLINE | ID: mdl-37424237
BACKGROUND AND OBJECTIVE: Some studies on maintenance hemodialysis (MHD) patients report a longer survival, albeit with poorer health-related quality of life (HRQoL), and more depression symptoms in women than in men. Whether these gender differences vary with age is uncertain. We tested the associations of gender with mortality, depression symptoms, and HRQoL in MHD patients of different age groups. METHODS: We used data from 1504 adult MHD patients enrolled in the PROHEMO, a prospective cohort in Salvador, Brazil. The KDQOL-SF was used for the component summaries of the mental (MCS) and physical (PCS) HRQoL scales. Depression symptoms were assessed by the complete version of the Center for Epidemiological Studies Depression Screening Index (CES-D). To test for gender differences, extensively adjusted linear models were used for depression and HRQoL scores, and Cox models for death hazard ratio (HR). RESULTS: Women reported worse HRQoL than men, particularly for ages ⩾60 years. In the age group ⩾60 years, the adjusted difference (AD) in score was -3.45; 95% CI: -6.81, -0.70 for MCS -3.16; -5.72, -0.60 for PCS. Older (⩾60 years) women also had more depression symptoms (AD 4.98; 2.33, 7.64). Mortality was slightly lower in women than in men with an adjusted HR of 0.89 (0.71, 1.11) and consistent across age categories. CONCLUSIONS: In a sample of Brazilian MHD patients, women had a slightly lower mortality, albeit with more depression symptoms and poorer HRQoL than men, particularly among older patients. This study highlights the need to investigate gender inequalities for MHD patients across different cultures and populations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Depressão Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality / Patient_preference Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Artif Organs Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Depressão Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality / Patient_preference Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Artif Organs Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos