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Intravenous prostaglandin E1 (alprostadil) bolus in ductus arteriosus-dependent CHD: valid or absolutely contraindicated?
Colín Ortiz, Jose L; Cruz Hernández, Angel; Silva Estrada, Jorge A; Maldonado Alonso, Roberto; Corona Villalobos, Carlos A; González Rebeles Guerrero, Carlos; Pérez Pérez, Linda F.
Afiliação
  • Colín Ortiz JL; Department of Paediatric Cardiology, National Institute of Paediatrics, Coyoacan, Mexico City, Mexico.
  • Cruz Hernández A; Department of Paediatric Cardiology, National Institute of Paediatrics, Coyoacan, Mexico City, Mexico.
  • Silva Estrada JA; Department of Paediatric Cardiology, National Institute of Paediatrics, Coyoacan, Mexico City, Mexico.
  • Maldonado Alonso R; Department of Pediatric Cardiology, Hospital of the Poblano Child, Puebla, Mexico.
  • Corona Villalobos CA; Department of Paediatric Cardiology, National Institute of Paediatrics, Coyoacan, Mexico City, Mexico.
  • González Rebeles Guerrero C; Department of Paediatric Cardiology, National Institute of Paediatrics, Coyoacan, Mexico City, Mexico.
  • Pérez Pérez LF; Department of Pediatric Cardiology, Hospital of the Poblano Child, Puebla, Mexico.
Cardiol Young ; 34(2): 314-318, 2024 Feb.
Article em En | MEDLINE | ID: mdl-37403735
The use of prostaglandin E1 is well documented in ductus arteriosus-dependent CHD or in neonatal pulmonary pathologies that cause severe pulmonary hypertension. The intravenous infusion is well established in loading infusion and maintenance with an onset of action of 30 minutes until 2 hours or even more. Our aim is to report three patients with pulmonary atresia that presented hypercyanotic spell due to a ductal spasm during cardiac catheterisation in whom the administration of a bolus of alprostadil reversed the spasm and increased pulmonary flow, immediately stabilising the condition of the patients allowing subsequent successful stent placement with no serious complications or sequelae after the administration of the bolus. More studies are needed to make a recommendation regarding the use of alprostadil in bolus in cases where the ductal spasm might jeopardise the life of the patient.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canal Arterial / Permeabilidade do Canal Arterial / Cardiopatias Congênitas Limite: Humans / Newborn Idioma: En Revista: Cardiol Young Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / PEDIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canal Arterial / Permeabilidade do Canal Arterial / Cardiopatias Congênitas Limite: Humans / Newborn Idioma: En Revista: Cardiol Young Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / PEDIATRIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido