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Association of vitamin D and cognition in people with type 2 diabetes: a systematic review.
da Silva, Alice D; Oliveira, Julia S; de Castro, Isabela C; Paiva, Wanderléia C; Gomes, Júnia M G; Pimenta, Laura C J P.
Afiliação
  • da Silva AD; Department of Nutrition, Universidade Federal de Lavras, Minas Gerais, Brazil.
  • Oliveira JS; Department of Nutrition and Health, Universidade Federal de Viçosa, Minas Gerais, Brazil.
  • de Castro IC; Department of Nutrition, Universidade Federal de Lavras, Minas Gerais, Brazil.
  • Paiva WC; Instituto Federal de Educação, Ciência e Tecnologia do Sudeste de Minas Gerais, Minas Gerais, Brazil.
  • Gomes JMG; Instituto Federal de Educação, Ciência e Tecnologia do Sudeste de Minas Gerais, Minas Gerais, Brazil.
  • Pimenta LCJP; Department of Nutrition, Universidade Federal de Lavras, Minas Gerais, Brazil.
Nutr Rev ; 82(5): 622-638, 2024 Apr 12.
Article em En | MEDLINE | ID: mdl-37403328
CONTEXT: There is a high prevalence of vitamin D deficiency and impaired cognitive function in people with type 2 diabetes mellitus (T2DM). OBJECTIVE: To critically and systematically review the literature on the association between vitamin D status and cognitive performance in people with type 2 diabetes. DATA SOURCES: This review was conducted according to PRISMA recommendations. MEDLINE, SCOPUS, the Cochrane Library, and Web of Science databases were searched using the terms "Diabetes Mellitus, Type 2", "Cognitive Function", and "Vitamin D". DATA EXTRACTION: Eight observational and 1 randomized study were included, containing data of 14 648 adult and elderly individuals (19-74 y). All extracted data were compiled, compared, and critically analyzed. DATA ANALYSIS: There is no strong evidence that lower serum concentrations of vitamin D and vitamin D-binding protein are associated with worsening cognitive function in individuals with T2DM. Vitamin D supplementation (12 wk) improved the scores of some executive functioning tests, although there was no difference between low doses (5000 IU/wk) and high doses (50 000 IU/wk). CONCLUSIONS: There is no high-quality evidence demonstrating an association between vitamin D status and cognitive function, or clinical benefits on cognition from vitamin D supplementation in individuals with T2DM. Future studies are needed. Systematic Review Registration: PROSPERO registration no. CRD42021261520.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Guideline / Risk_factors_studies / Systematic_reviews Limite: Adult / Aged / Humans Idioma: En Revista: Nutr Rev Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Guideline / Risk_factors_studies / Systematic_reviews Limite: Adult / Aged / Humans Idioma: En Revista: Nutr Rev Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos