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Postsurgical outcomes in a cohort of patients with hippocampal sclerosis: Initial experience in a referral epilepsy center in Peru.
De La Cruz Ramirez, Walter F; Chacón Zuñiga, Denisse E; Sánchez-Boluarte, Sofía S; Vásquez Perez, Carlos M; Nuñez Del Prado Murillo, Liza N; Delgado Rios, José C.
Afiliação
  • De La Cruz Ramirez WF; Epilepsy Department, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
  • Chacón Zuñiga DE; Epilepsy Department, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
  • Sánchez-Boluarte SS; Epilepsy Department, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
  • Vásquez Perez CM; School of Medicine, Universidad Cesar Vallejo, Trujillo, Perú.
  • Nuñez Del Prado Murillo LN; Neurosurgery Department, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
  • Delgado Rios JC; Epilepsy Department, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.
Epilepsia Open ; 8(3): 1175-1181, 2023 09.
Article em En | MEDLINE | ID: mdl-37394997
Mesial temporal lobe epilepsy, one of the most common forms of epilepsy, is often linked with drug resistance. Surgical intervention is a reliable and safe treatment option, though research into postsurgical outcomes in our locality remains limited. We performed a retrospective observational study included 91 patients with mesial temporal lobe epilepsy and hippocampal sclerosis who had undergone anterior temporal lobectomy between 2012 and 2020 at a surgical epilepsy center located in Lima, Peru. Postoperative outcomes were analyzed using bivariate and multivariate analysis based on the Engel classification. We found that after 12 months of follow-up, 78.65% of the 91 patients achieved an Engel IA classification, while 9.09% attained Engel IB classification and 11.24% were designated as Engel II, with only 1.12% classified as Engel IVA. The median QOLIE31 score was 84 (IQR: 75-90), with 74.16% of the participants successfully reintegrating into academic or employment activities. After 24 months, only 68 patients completed the follow-up, with 69.12% achieving an Engel IA classification. Individuals with a secondary education or higher were more likely to achieve an Engel IA classification at 12 months (OR: 5.11; P = 0.005; CI: 1.63-16.01), after adjusting for sex and age. We concluded that most patients exhibited favorable outcomes after 1 year of follow-up. However, lower educational attainment was linked to worse postsurgical outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epilepsia do Lobo Temporal / Esclerose Hipocampal Tipo de estudo: Observational_studies Limite: Humans País/Região como assunto: America do sul / Peru Idioma: En Revista: Epilepsia Open Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epilepsia do Lobo Temporal / Esclerose Hipocampal Tipo de estudo: Observational_studies Limite: Humans País/Região como assunto: America do sul / Peru Idioma: En Revista: Epilepsia Open Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos