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Clinical management of salivary gland hypofunction in patients with head and neck cancer: a scoping review of physical salivary stimulation methods.
Coelho, Camila Pinho E Souza; de Melo, Jéssica Luiza Mendonça Albuquerque; Nunes, Fernanda de Paula E Silva; Guimarães, Maria do Carmo Machado; Heller, Debora; Grisi, Daniela Corrêa; Dame-Teixeira, Naile.
Afiliação
  • Coelho CPES; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil.
  • de Melo JLMA; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil.
  • Nunes FPES; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil.
  • Guimarães MDCM; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil.
  • Heller D; Post Graduate Program in Dentistry, Cruzeiro do Sul University, São Paulo, Brazil; Experimental Research, Hospital Israelita Albert Einstein, São Paulo, Brazil; Department of Periodontology, UT Health San Antonio, San Antonio, TX, USA.
  • Grisi DC; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil.
  • Dame-Teixeira N; Department of Dentistry, School of Health Sciences, University of Brasília, Brasília, Brazil; Division of Oral Biology, School of Dentistry, University of Leeds, UK. Electronic address: Nailedame@unb.br.
Article em En | MEDLINE | ID: mdl-37380576
OBJECTIVE(S): This scoping review aims to map the scientific literature on the therapies currently available for physical salivary stimulation in individuals with hyposalivation caused by radiotherapy. STUDY DESIGN: Studies were included when they comprised the target population of adult individuals receiving radiotherapy of the head and neck region and who developed or were at risk of developing hyposalivation. Two reviewers selected the studies and extracted data on the type of physical salivary stimulation therapy used, the degree of glandular tissue involvement, and the percentage of salivary flow alteration. Therapies were classified according to either prophylactic application (before/during radiotherapy) or therapeutic application (post-radiotherapy). RESULTS: Sixteen articles were included: 4 tested transcutaneous electrical nerve stimulation (TENS), 3 studied low-level lasers, 7 researched acupunctures, and 2 investigated acupuncture-like TENS. The outcomes of the prophylactic studies indicated beneficial effects (similar salivary flow or reduced salivary flow loss), although most studies did not include a comparable control group. Therapeutic studies presented conflicting results. CONCLUSION(S): Prophylactic therapies of physical salivary stimulation may produce better effects than therapeutic applications. However, the protocols best indicated could not be defined. Well-designed, controlled clinical trials should be researched in the future to support the clinical recommendation of any of these treatments.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xerostomia / Estimulação Elétrica Nervosa Transcutânea / Neoplasias de Cabeça e Pescoço Tipo de estudo: Etiology_studies / Guideline / Systematic_reviews Limite: Adult / Humans Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xerostomia / Estimulação Elétrica Nervosa Transcutânea / Neoplasias de Cabeça e Pescoço Tipo de estudo: Etiology_studies / Guideline / Systematic_reviews Limite: Adult / Humans Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos