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Severe Combined Immunodeficiency-Classification, Microbiology Association and Treatment.
Justiz-Vaillant, Angel A; Gopaul, Darren; Akpaka, Patrick Eberechi; Soodeen, Sachin; Arozarena Fundora, Rodolfo.
Afiliação
  • Justiz-Vaillant AA; Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
  • Gopaul D; Department of Internal Medicine, Port of Spain General Hospital, The University of the West Indies, St. Augustine, Trinidad and Tobago.
  • Akpaka PE; Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
  • Soodeen S; Eric Williams Medical Sciences Complex, North Central Regional Health Authority, Champs Fleurs, Trinidad and Tobago.
  • Arozarena Fundora R; Department of Paraclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Microorganisms ; 11(6)2023 Jun 15.
Article em En | MEDLINE | ID: mdl-37375091
Severe combined immunodeficiency (SCID) is a primary inherited immunodeficiency disease that presents before the age of three months and can be fatal. It is usually due to opportunistic infections caused by bacteria, viruses, fungi, and protozoa resulting in a decrease in number and impairment in the function of T and B cells. Autosomal, X-linked, and sporadic forms exist. Evidence of recurrent opportunistic infections and lymphopenia very early in life should prompt immunological investigation and suspicion of this rare disorder. Adequate stem cell transplantation is the treatment of choice. This review aimed to provide a comprehensive approach to the microorganisms associated with severe combined immunodeficiency (SCID) and its management. We describe SCID as a syndrome and summarize the different microorganisms that affect children and how they can be investigated and treated.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Microorganisms Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Microorganisms Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Suíça