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Esophageal Neuroendocrine Carcinoma Presenting After Definitive Chemoradiation of Squamous Cell Carcinoma in the Same Location.
Prenatt, Zarian; Liaquat, Hammad; Shupp, Brittney; Stoll, Lisa; Schneider, Yecheskel.
Afiliação
  • Prenatt Z; Department of Internal Medicine, St. Luke's University Health Network, Bethlehem, PA.
  • Liaquat H; Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA.
  • Shupp B; Department of Internal Medicine, St. Luke's University Health Network, Bethlehem, PA.
  • Stoll L; Department of Pathology, St. Luke's University Health Network, Bethlehem, PA.
  • Schneider Y; Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA.
ACG Case Rep J ; 10(6): e01091, 2023 Jun.
Article em En | MEDLINE | ID: mdl-37346465
Esophageal neuroendocrine carcinoma is very rare and highly aggressive. An 85-year-old man with a history of esophageal squamous cell carcinoma in remission presented 4 years after definitive chemoradiation with new-onset dysphagia. Endoscopy with biopsy revealed high-grade malignancy consistent with neuroendocrine carcinoma. Treatment options were limited to chemotherapy because of his metastatic disease, and he unfortunately died 14 months after diagnosis. The occurrence of esophageal neuroendocrine carcinoma in a site of prior squamous cell carcinoma is very uncommon, and this likely represents a case of radiation-induced malignancy. Therefore, when undergoing radiotherapy, patients and providers should discuss the possibility of this life-threatening complication.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACG Case Rep J Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACG Case Rep J Ano de publicação: 2023 Tipo de documento: Article País de publicação: Estados Unidos