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Natural and Synthetic Peptides to Control Drug-resistant Pathogens.
de Sousa, Francisca J F; Costa, Igor R S; Cavalcante, Francisco L P; Silva, Ana J O; Brito, Daiane M S; da Silva, José Y G; Silva, José J L; Almeida, Camila G L; Mesquita, Felipe P; Souza, Pedro F N.
Afiliação
  • de Sousa FJF; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Costa IRS; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Cavalcante FLP; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Silva AJO; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Brito DMS; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • da Silva JYG; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Silva JJL; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Almeida CGL; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Mesquita FP; Department of Biochemistry and Molecular Biology, Sciences Center, Federal University of Cear, Campus do Pici, CEP-60440-554, Fortaleza, Ceará - CE, Brazil.
  • Souza PFN; Department of Physiology and Pharmacology, Drug Research and Development Center, Federal University of Ceará, Fortaleza, 60430-275, Brazil.
Curr Protein Pept Sci ; 24(7): 567-578, 2023.
Article em En | MEDLINE | ID: mdl-37345241
Due to the excessive and inappropriate use of antibiotics in farming and clinic, pathogens developed resistance mechanisms to currently used drugs. Thus, because of this resistance, drugs become ineffective, leading to public health problems worldwide. According to the World Health Organization (WHO), microbial resistance to drugs is one of the most threats that humanity must face. Therefore, it is imperative to seek alternative methods to overcome microbial resistance. Here, the potential of natural or synthetic antimicrobial peptides to overcome microbial resistance will be discussed, and how peptides could be a source for new therapeutics molecules. In this context, antimicrobial peptides (natural or synthetic) are considered promising molecules based on their antifungal, antiviral, and antibacterial properties, making them eligible for developing new drugs. In addition, they can act synergistically with existing drugs on the market, revealing a broad spectrum of applications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Antibacterianos Idioma: En Revista: Curr Protein Pept Sci Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Antibacterianos Idioma: En Revista: Curr Protein Pept Sci Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos