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Gingival metastasis of angiosarcoma of the breast as a first manifestation of spreading disease: Case report and review of the literature.
Mota, Maria Emília; Tomo, Saygo; Alves, Fábio de Abreu; Pellissari, Guilherme Andrade; do Nascimento, Antonio Geraldo; Lopes, Rodrigo Nascimento.
Afiliação
  • Mota ME; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • Tomo S; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • Alves FA; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • Pellissari GA; Department of Anatomic Pathology, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • do Nascimento AG; Department of Anatomic Pathology, A.C.Camargo Cancer Center, São Paulo, Brazil.
  • Lopes RN; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
Spec Care Dentist ; 44(2): 458-464, 2024.
Article em En | MEDLINE | ID: mdl-37341541
BACKGROUND: Angiosarcoma is an aggressive malignant neoplasm of vascular origin. Oral metastases of angiosarcoma are rare and have a non-specific clinical presentation, thus the diagnosis may be challenging. CASE REPORT: Herein we report a case of a 34-year-old female patient after treatment of a high-grade angiosarcoma of the breast, who presented an asymptomatic bleeding purplish nodule in the maxillary interdental papilla between the first and second premolar. A biopsy was performed, and the histological examination revealed infiltration by malignant neoplasm of epithelioid and fusocellular pattern. Immunohistochemical analysis demonstrated that neoplastic cells were positive for ERG and CD31, and negative for cytokeratins AE1/AE3, confirming the diagnosis of metastatic angiosarcoma. After investigation, multiple metastases were discovered. The patient is under management with chemotherapy and palliative radiotherapy for the bone lesions. CONCLUSION: Metastases should be considered in the differential diagnosis of oral lesions in patients with a previous history of cancer. Due to the morphology of angiosarcomas, the metastatic lesions may resemble benign vascular lesions, therefore, biopsy is mandatory to exclude malignancy.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Hemangiossarcoma Limite: Adult / Female / Humans Idioma: En Revista: Spec Care Dentist Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Hemangiossarcoma Limite: Adult / Female / Humans Idioma: En Revista: Spec Care Dentist Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos