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Coffee intake one hour prior to phlebotomy produces no clinically significant changes in routine biochemical test results.
Benozzi, Silvia F; Unger, Gisela; Campion, Amparo; Milano, Pablo G; Pennacchiotti, Graciela L.
Afiliação
  • Benozzi SF; Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS), Bahía Blanca, Argentina.
  • Unger G; Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS), Bahía Blanca, Argentina.
  • Campion A; Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS), Bahía Blanca, Argentina.
  • Milano PG; Hospital Municipal de Agudos "Dr. Leónidas Lucero", Bahía Blanca, Argentina.
  • Pennacchiotti GL; Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS), Bahía Blanca, Argentina.
Biochem Med (Zagreb) ; 33(2): 020705, 2023 Jun 15.
Article em En | MEDLINE | ID: mdl-37324115
Introduction: Although current guidelines recommend not drinking coffee prior to phlebotomy, our hypothesis is that drinking coffee does not affect the clinical interpretation of biochemical and haematological test results. Materials and methods: Twenty-seven volunteers were studied in basal state (T0) and 1h after (T1) drinking coffee. Routine haematological (Sysmex-XN1000 analyser) and biochemistry parameters (Vitros 4600 analyser) were studied. Results were compared using the Wilcoxon test (P < 0.05). A clinical change was considered when mean percent difference (MD%) was higher than the reference change value (RCV). Results: Coffee intake produced statistically, but not clinically, significant: i) increases in haemoglobin (P = 0.009), mean cell haemoglobin concentration (P = 0.044), neutrophils (P = 0.001), albumin (P = 0.001), total protein (P = 0.000), cholesterol (P = 0.025), high density lipoprotein cholesterol (P = 0.007), uric acid (P = 0.011), calcium (P = 0.001), potassium (P = 0.010), aspartate aminotransferase (P = 0.001), amylase (P = 0.026), and lactate dehydrogenase (P = 0.001), and ii) decreases in mean cell volume (P = 0.002), red cell distribution width (P = 0.001), eosinophils (P = 0.002), and lymphocytes (P = 0.001), creatinine (P = 0.001), total bilirubin (P = 0.012), phosphorus (P = 0.001), magnesium (P = 0.007), and chloride (P = 0.001). Conclusion: Drinking a cup of coffee 1 hour prior to phlebotomy produces no clinically significant changes in routine biochemical and haematological test results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flebotomia / Testes Hematológicos Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Biochem Med (Zagreb) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Argentina País de publicação: Croácia
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flebotomia / Testes Hematológicos Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Biochem Med (Zagreb) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Argentina País de publicação: Croácia