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Hepatitis C virus genotype diversity in Ningxia Hui autonomous region, Northwestern China.
An, C; Ma, W; He, R F; Wu, T; Shi, J N; Sun, T T; Piao, W H.
Afiliação
  • An C; People's Hospital of Ningxia Hui Autonomous Region, Department of Laboratory Medicine, Yinchuan, Ningxia, China.
  • Ma W; People's Hospital of Ningxia Hui Autonomous Region, Department of Laboratory Medicine, Yinchuan, Ningxia, China.
  • He RF; People's Hospital of Ningxia Hui Autonomous Region, Department of Laboratory Medicine, Yinchuan, Ningxia, China.
  • Wu T; People's Hospital of Ningxia Hui Autonomous Region, Department of Laboratory Medicine, Yinchuan, Ningxia, China.
  • Shi JN; Ningxia Medical Uniwersity, College of Clincal Medicine, Yinchuan, Ningxia, China.
  • Sun TT; Ningxia Medical Uniwersity, College of Clincal Medicine, Yinchuan, Ningxia, China.
  • Piao WH; People's Hospital of Ningxia Hui Autonomous Region, Department of Laboratory Medicine, Yinchuan, Ningxia, China.
Braz J Biol ; 83: e267641, 2023.
Article em En | MEDLINE | ID: mdl-37255197
Hepatitis C virus (HCV) genotypes vary greatly in different regions. The aim of this study is to investigate the distribution of HCV genotypes in HCV infected patients, in Ningxia Hui Autonomous Region. Nucleic acid extraction and amplification were performed with test kits on 153 HCV infected patients serum samples. The HCV viral load was measured using reverse transcriptase PCR (RT-PCR) and HCV genotypes were determined. Among the 153 HCV-infected patients, 56 had genotype (GT)1b (36.60%), 45 had GT2a (29.40%), 23 had GT3a (15.00%), 14 had GT3b (9.20%),13 had GT6a (8.50%), 1 had GT1g (0.70%), 1 had GT6xa (0.70%). In GT1b, 21.40% were female and 78.60% were male; in GT2a, 42.20% were female and 57.80% were male;Males were most prevalent in genotypes 1b(39.30%), while female were most prevalent in genotype 2a(46.30%). Rare GT1g and GT6xa were also detected in males. The 41-50 year age group had the highest HCV prevalence of 32.00%. HCV GT1b is the predominant HCV genotype in Ningxia Hui Autonomous Region.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C / Hepacivirus Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Braz J Biol Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Brasil
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C / Hepacivirus Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: Asia Idioma: En Revista: Braz J Biol Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Brasil