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Hilab System Device in an Oncological Hospital: A New Clinical Approach for Point of Care CBC Test, Supported by the Internet of Things and Machine Learning.
Gasparin, Aléxia Thamara; Araujo, Claudiane Isabel Franco; Cardoso, Mônica Ribas; Schmitt, Patricia; Godoy, Juliana Beker; Reichert, Eduarda Silva; Pimenta, Maria Eduarda; Gonçalves, Caroline Bretas; Santiago, Erika Bergamo; Silva, Ivan Lucas Reis; Gaideski, Bruno de Paula; Cardoso, Milena Andreuzo; Silva, Fernanda D'Amico; Sommer, Viviane da Rosa; Hartmann, Luis Felipe; Perazzoli, Carolina Rodrigues de Araujo; Farias, João Samuel de Holanda; Beltrame, Olair Carlos; Winter, Nicole; Nicollete, Diego Rinaldi Pavesi; Lopes, Silvia Nathalia Bueno; Predebon, João Victor; Almeida, Bernardo Montesanti Machado de; Rogal Júnior, Sérgio Renato; Figueredo, Marcus Vinícius Mazega.
Afiliação
  • Gasparin AT; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Araujo CIF; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Cardoso MR; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Schmitt P; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Godoy JB; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Reichert ES; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Pimenta ME; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Gonçalves CB; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Santiago EB; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Silva ILR; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Gaideski BP; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Cardoso MA; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Silva FD; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Sommer VDR; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Hartmann LF; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Perazzoli CRA; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Farias JSH; Erasto Gaertner Hospital, Curitiba 81520-060, PR, Brazil.
  • Beltrame OC; Erasto Gaertner Hospital, Curitiba 81520-060, PR, Brazil.
  • Winter N; Erasto Gaertner Hospital, Curitiba 81520-060, PR, Brazil.
  • Nicollete DRP; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Lopes SNB; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Predebon JV; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Almeida BMM; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Rogal Júnior SR; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
  • Figueredo MVM; Department of Research and Development, Hilab, Jose Altair Possebom, 800, Curitiba 81270-185, PR, Brazil.
Diagnostics (Basel) ; 13(10)2023 May 11.
Article em En | MEDLINE | ID: mdl-37238184
The complete blood count (CBC) is a highly requested test that is generally restricted to centralized laboratories, which are limited by high cost, being maintenance-demanding, and requiring costly equipment. The Hilab System (HS) is a small, handheld hematological platform that uses microscopy and chromatography techniques, combined with machine learning (ML) and artificial intelligence (AI), to perform a CBC test. This platform uses ML and AI techniques to add higher accuracy and reliability to the results besides allowing for faster reporting. For clinical and flagging capability evaluation of the handheld device, the study analyzed 550 blood samples of patients from a reference institution for oncological diseases. The clinical analysis encompassed the data comparison between the Hilab System and a conventional hematological analyzer (Sysmex XE-2100) for all CBC analytes. The flagging capability study compared the microscopic findings from the Hilab System and the standard blood smear evaluation method. The study also assessed the sample collection source (venous or capillary) influences. The Pearson correlation, Student t-test, Bland-Altman, and Passing-Bablok plot of analytes were calculated and are shown. Data from both methodologies were similar (p > 0.05; r ≥ 0.9 for most parameters) for all CBC analytes and flagging parameters. Venous and capillary samples did not differ statistically (p > 0.05). The study indicates that the Hilab System provides humanized blood collection associated with fast and accurate data, essential features for patient wellbeing and quick physician decision making.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Diagnostics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Diagnostics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça