Palmitic acid-induced microRNA-143-5p expression promotes the epithelial-mesenchymal transition of retinal pigment epithelium via negatively regulating JDP2.

Tian, Yunlin; Shao, Juan; Bai, Shuwei; Xu, Zhiguo; Bi, Chunchao

Tian, Yunlin; Shao, Juan; Bai, Shuwei; Xu, Zhiguo; Bi, Chunchao.

Afiliação

Tian Y; Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.
Shao J; Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.
Bai S; Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.
Xu Z; Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.
Bi C; Department of Ophthalmology, Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.

Aging (Albany NY) ; 15(9): 3465-3479, 2023 04 25.

Article em En | MEDLINE | ID: mdl-37179125

Assuntos

MicroRNAs; Vitreorretinopatia Proliferativa; Humanos; Epitélio Pigmentado da Retina/patologia; Vitreorretinopatia Proliferativa/genética; Vitreorretinopatia Proliferativa/metabolismo; Vitreorretinopatia Proliferativa/patologia; Ácido Palmítico/toxicidade; Transição Epitelial-Mesenquimal/genética; MicroRNAs/metabolismo; Caderinas/metabolismo; Movimento Celular/genética; Proteínas Repressoras/metabolismo

Palavras-chave

JDP2; epithelialmesenchymal transition (EMT); miR-143-5p; retinal pigment epithelial (RPE) cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitreorretinopatia Proliferativa / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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