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Lab-made 3D-printed electrochemical sensors for tetracycline determination.
Lopes, Carlos E C; de Faria, Lucas V; Araújo, Diele A G; Richter, Eduardo M; Paixão, Thiago R L C; Dantas, Luiza M F; Muñoz, Rodrigo A A; da Silva, Iranaldo S.
Afiliação
  • Lopes CEC; Chemistry Technology Department, Federal University of Maranhão, 65080-805, São Luís, Maranhão, Brazil.
  • de Faria LV; Institute of Chemistry, Federal University of Uberlândia, 38408-100, Uberlândia, MG, Brazil.
  • Araújo DAG; Institute of Chemistry, Department of Fundamental Chemistry, University of São Paulo, 05508-000, São Paulo, SP, Brazil.
  • Richter EM; Institute of Chemistry, Federal University of Uberlândia, 38408-100, Uberlândia, MG, Brazil.
  • Paixão TRLC; Institute of Chemistry, Department of Fundamental Chemistry, University of São Paulo, 05508-000, São Paulo, SP, Brazil.
  • Dantas LMF; Chemistry Technology Department, Federal University of Maranhão, 65080-805, São Luís, Maranhão, Brazil.
  • Muñoz RAA; Institute of Chemistry, Federal University of Uberlândia, 38408-100, Uberlândia, MG, Brazil. Electronic address: munoz@ufu.br.
  • da Silva IS; Chemistry Technology Department, Federal University of Maranhão, 65080-805, São Luís, Maranhão, Brazil. Electronic address: iranaldo.ss@ufma.br.
Talanta ; 259: 124536, 2023 Jul 01.
Article em En | MEDLINE | ID: mdl-37062090
Antibiotics such as tetracycline (TC) are widely prescribed to treat humans or dairy animals. Therefore, it is important to establish affordable devices in laboratories with minimal infrastructure. 3D printing has proven to be a powerful and cost-effective tool that revolutionizes many applications in electrochemical sensing. In this work, we employ a conductive filament based on graphite (Gr) and polylactic acid (PLA) (40:60; w/w; synthesized in our lab) to manufacture 3D-printed electrodes. This electrode was used "as printed" and coupled to batch injection analysis with amperometric detection (BIA-AD) for TC sensing. Preliminary studies by cyclic voltammetry and differential pulse voltammetry revealed a mass transport governed by adsorption of the species and consequent fouling of the redox products on the 3D printed surface. Thus, a simple strategy (solution stirring and application of successive potentials, +0.95 V followed by +1.2 V) was associated with the BIA-AD system to solve this effect. The proposed electrode showed analytical performance comparable to costly conventional electrodes with linear response ranging from 0.5 to 50 µmol L-1 and a detection limit of 0.19 µmol L-1. Additionally, the developed method was applied to pharmaceutical, tap water, and milk samples, which required minimal sample preparation (simple dilution). Recovery values of 92-117% were obtained for tap water and milk samples, while the content found of TC in the capsule was close to the value reported by the manufacturer. These results indicate the feasibility of the method for routine analysis involving environmental, pharmaceutical, and food samples.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetraciclina / Laboratórios Limite: Animals / Humans Idioma: En Revista: Talanta Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetraciclina / Laboratórios Limite: Animals / Humans Idioma: En Revista: Talanta Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda