Your browser doesn't support javascript.
loading
Pneumocystis jirovecii Colonization in Mexican Patients with Chronic Obstructive Pulmonary Disease.
Plascencia-Cruz, Marcela; Plascencia-Hernández, Arturo; De Armas-Rodríguez, Yaxsier; Cervantes-Guevara, Gabino; Cervantes-Cardona, Guillermo Alonso; Ramírez-Ochoa, Sol; González-Ojeda, Alejandro; Fuentes-Orozco, Clotilde; Hernández-Mora, Francisco Javier; González-Valencia, Carlos Miguel; Pérez de Acha-Chávez, Andrea; Cervantes-Pérez, Enrique.
Afiliação
  • Plascencia-Cruz M; Department of Internal Medicine, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
  • Plascencia-Hernández A; Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Jalisco, Mexico.
  • De Armas-Rodríguez Y; Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Jalisco, Mexico.
  • Cervantes-Guevara G; Department of Pediatric Infectious Diseases, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
  • Cervantes-Cardona GA; Molecular Biology Laboratory, Instituto de Medicina Tropical "Pedro Kourí", La Habana 11400, Cuba.
  • Ramírez-Ochoa S; Department of Welfare and Sustainable Development, Centro Universitario del Norte, Universidad de Guadalajara, Colotlán 46200, Jalisco, Mexico.
  • González-Ojeda A; Department of Gastroenterology, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
  • Fuentes-Orozco C; Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Jalisco, Mexico.
  • Hernández-Mora FJ; Department of Internal Medicine, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
  • González-Valencia CM; Biomedical Research Unit 02, Specialties Hospital of the Western National Medical Center, Mexican Institute of Social Security, Guadalajara 44329, Jalisco, Mexico.
  • Pérez de Acha-Chávez A; Biomedical Research Unit 02, Specialties Hospital of the Western National Medical Center, Mexican Institute of Social Security, Guadalajara 44329, Jalisco, Mexico.
  • Cervantes-Pérez E; Human Reproduction, Growth and Child Development Clinic, Health Sciences University Center, Universidad de Guadalajara, Guadalajara 44100, Jalisco, Mexico.
Trop Med Infect Dis ; 8(3)2023 Feb 24.
Article em En | MEDLINE | ID: mdl-36977138
The prevalence of colonization by Pneumocystis jirovecii (P. jirovecii) has not been studied in Mexico. We aimed to determine the prevalence of colonization by P. jirovecii using molecular detection in a population of Mexican patients with chronic obstructive pulmonary disease (COPD) and describe their clinical and sociodemographic profiles. We enrolled patients discharged from our hospital diagnosed with COPD and without pneumonia (n = 15). The primary outcome of this study was P. jirovecii colonization at the time of discharge, as detected by nested polymerase chain reaction (PCR) of oropharyngeal wash samples. The calculated prevalence of colonization for our study group was 26.66%. There were no statistically significant differences between COPD patients with and without colonization in our groups. Colonization of P. jirovecii in patients with COPD is frequent in the Mexican population; the clinical significance, if any, remains to be determined. Oropharyngeal wash and nested PCR are excellent cost-effective options to simplify sample collection and detection in developing countries and can be used for further studies.
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies País/Região como assunto: Mexico Idioma: En Revista: Trop Med Infect Dis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies País/Região como assunto: Mexico Idioma: En Revista: Trop Med Infect Dis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México País de publicação: Suíça