Your browser doesn't support javascript.
loading
Oral lichen planus: case series and experience in a tertiary dermatology service in Brazil.
Erthal, Aline; Lourenço, Silvia Vanessa; Nico, Marcello Menta Simonsen.
Afiliação
  • Erthal A; Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.
  • Lourenço SV; Department of Pathology, Faculty of Dentistry, Universidade de São Paulo, São Paulo, SP, Brazil.
  • Nico MMS; Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: mentanico@hotmail.com.
An Bras Dermatol ; 98(4): 493-497, 2023.
Article em En | MEDLINE | ID: mdl-36964105
BACKGROUND: Lichen planus is an inflammatory disease that can affect both the skin and mucous membranes, including the oral mucosa. There is very little original Brazilian dermatology literature about oral lichen planus. OBJECTIVE: To describe the clinical, pathological, and treatment data of 201 patients diagnosed with oral lichen planus followed at the Stomatology Outpatient Clinic of Hospital das Clínicas, Universidade de São Paulo, from 2003 to 2021. METHOD: The patients demographic profile, the morpho-topographic features of the lesions, the treatment employed, and the possible presence of squamous cell carcinoma were analyzed. RESULTS: The disease was more common in women over 50 years of age, tending to be chronic, with a large number of cases showing cicatricial sequelae in the mucosa. Topical treatment with potent corticosteroids was shown to be effective in the vast majority of cases. Squamous cell carcinoma in oral lichen planus cicatricial sequelae was observed in eight cases. STUDY LIMITATIONS: Retrospective study of medical records, with gaps regarding the filling out of data; unequal observation time among the studied cases. CONCLUSIONS: This is the largest Brazilian dermatology series on oral lichen planus. The response to topical corticoid therapy was excellent in the vast majority of cases. The high prevalence of atrophic lesions, demonstrating the chronicity and tissue destruction potential of this disease, may explain the large number of cases of squamous cell carcinoma.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Líquen Plano Bucal / Dermatologia / Líquen Plano Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: An Bras Dermatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Líquen Plano Bucal / Dermatologia / Líquen Plano Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Female / Humans / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: An Bras Dermatol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha