Both osmolality-dependent and independent mechanisms are associated with acute hyperglycemia-induced cardiovascular adverse reactions: Analysis of the mutual interactions leading to cardiovascular phenotypes in dogs.

Kambayashi, Ryuichi; Izumi-Nakaseko, Hiroko; Goto, Ai; Takei, Yoshinori; Matsumoto, Akio; Lorch, Ulrike; Täubel, Jörg; Sugiyama, Atsushi

Kambayashi, Ryuichi; Izumi-Nakaseko, Hiroko; Goto, Ai; Takei, Yoshinori; Matsumoto, Akio; Lorch, Ulrike; Täubel, Jörg; Sugiyama, Atsushi.

Afiliação

Kambayashi R; Department of Pharmacology, Faculty of Medicine, Toho University.
Izumi-Nakaseko H; Department of Pharmacology, Faculty of Medicine, Toho University.
Goto A; Department of Pharmacology, Faculty of Medicine, Toho University.
Takei Y; Department of Pharmacology, Faculty of Medicine, Toho University.
Matsumoto A; Department of Aging Pharmacology, Faculty of Medicine, Toho University.
Lorch U; Richmond Research Institute, St George's University of London Cranmer Terrace, UK.
Täubel J; Richmond Research Institute, St George's University of London Cranmer Terrace, UK.
Sugiyama A; Department of Pharmacology, Faculty of Medicine, Toho University.

J Toxicol Sci ; 48(3): 169-178, 2023.

Article em En | MEDLINE | ID: mdl-36858642

Assuntos

Sistema Cardiovascular; Hiperglicemia; Cães; Animais; Glucose; Manitol; Fenótipo

Palavras-chave

Hyperglycemia; Hyperosmolality; Insulin; Mannitol; QT prolongation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistema Cardiovascular / Hiperglicemia Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: J Toxicol Sci Ano de publicação: 2023 Tipo de documento: Article País de publicação: Japão

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