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Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Danielli, Sara G; Porpiglia, Ermelinda; De Micheli, Andrea J; Navarro, Natalia; Zellinger, Michael J; Bechtold, Ingrid; Kisele, Samanta; Volken, Larissa; Marques, Joana G; Kasper, Stephanie; Bode, Peter K; Henssen, Anton G; Gürgen, Dennis; Delattre, Olivier; Surdez, Didier; Roma, Josep; Bühlmann, Peter; Blau, Helen M; Wachtel, Marco; Schäfer, Beat W.
Afiliação
  • Danielli SG; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Porpiglia E; Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • De Micheli AJ; Department of Biomedicine, Aarhus University, Aarhus C 8000, Denmark.
  • Navarro N; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Zellinger MJ; Laboratory of Translational Research in Child and Adolescent Cancer, Vall d'Hebron Research Institute, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona 08035, Spain.
  • Bechtold I; Seminar for Statistics, ETH Zürich, Zürich 8092, Switzerland.
  • Kisele S; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Volken L; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Marques JG; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Kasper S; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Bode PK; Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zürich 8032, Switzerland.
  • Henssen AG; Department of Pathology, University Hospital Zurich, Zurich, Switzerland.
  • Gürgen D; Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin 13353, Germany.
  • Delattre O; EPO Experimental Pharmacology and Oncology Berlin-Buch GmbH Berlin 13125, Germany.
  • Surdez D; INSERM U830, Équipe Labellisée LNCC, Diversity and Plasticity of Childhood Tumors Laboratory, PSL Research University, SIREDO Oncology Center, Institut Curie Research Center, Paris 75005, France.
  • Roma J; INSERM U830, Équipe Labellisée LNCC, Diversity and Plasticity of Childhood Tumors Laboratory, PSL Research University, SIREDO Oncology Center, Institut Curie Research Center, Paris 75005, France.
  • Bühlmann P; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland.
  • Blau HM; Laboratory of Translational Research in Child and Adolescent Cancer, Vall d'Hebron Research Institute, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona 08035, Spain.
  • Wachtel M; Seminar for Statistics, ETH Zürich, Zürich 8092, Switzerland.
  • Schäfer BW; Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sci Adv ; 9(6): eade9238, 2023 02 10.
Article em En | MEDLINE | ID: mdl-36753540
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Rabdomiossarcoma Alveolar / Antineoplásicos Limite: Child / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Rabdomiossarcoma Alveolar / Antineoplásicos Limite: Child / Humans Idioma: En Revista: Sci Adv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos