Your browser doesn't support javascript.
loading
Incorporation of zinc into cetylpyridinium chloride mouthwash affects the composition of multispecies biofilms.
Torrez, Willy Bustillos; Figueiredo, Luciene Cristina; Santos, Thalita Dias Silva; Soares, Geisla Mary; Pingueiro, João Marcos Spessoto; Pereira da Silva, Hélio Doyle; Malheiros, Zilson; Stewart, Bernal; Feres, Magda; Bueno-Silva, Bruno.
Afiliação
  • Torrez WB; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Figueiredo LC; Latin American Oral Health Association, São Paulo, São Paulo, Brazil.
  • Santos TDS; Research Department, Universidad Privada Franz Tamayo (UNIFRANZ), Cochabamba, Bolivia.
  • Soares GM; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Pingueiro JMS; Latin American Oral Health Association, São Paulo, São Paulo, Brazil.
  • Pereira da Silva HD; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Malheiros Z; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Stewart B; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Feres M; Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
  • Bueno-Silva B; Latin American Oral Health Association, São Paulo, São Paulo, Brazil.
Biofouling ; 39(1): 1-7, 2023 01.
Article em En | MEDLINE | ID: mdl-36656051
This study evaluated the effect of a mouthwash containing 0.075% cetylpyridinium chloride and 0.28% zinc lactate (CPC + Zn) in a multispecies biofilm model. A 7-days 33-species biofilm, formed on Calgary device, was 1-min treated with: 0.12% chlorhexidine (CHX), culture medium (negative control), 0.075% cetylpyridinium chloride (CPC) or CPC + Zn, 2x/day, from day 3 until day 6. The metabolic activity and the microbial composition were evaluated by colorimetric method and checkerboard DNA-DNA hybridization, respectively. The three antimicrobials (CPC, CPC + Zn and CHX) reduced metabolic activity, total biofilm count and several species counts, including Porphyromonas gingivalis, Fusobacterium nucleatum, Parvimonas micra, Campylobacter gracilis and Streptococcus mutans. However, only CPC + Zn reduced counts of the pathogen Prevotella intermedia and did not interfere with the levels of some beneficial species in relation to the negative control. The treatment of multispecies subgingival biofilm with CPC + Zn was effective in controlling periodontal pathogens and favored the colonization of health-associated bacterial species.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cetilpiridínio / Antissépticos Bucais Idioma: En Revista: Biofouling Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cetilpiridínio / Antissépticos Bucais Idioma: En Revista: Biofouling Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido