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Cutaneous Manifestations in Patients With COVID-19 Treated at a University Hospital in Southern Brazil.
Dupont, Letícia; Duquia, Rodrigo P; Pizutti, Gustavo W; Nunes, Fernanda B; Branchini, Gisele; Mosquera, Elsa Stella B; Bonamigo, Renan R.
Afiliação
  • Dupont L; Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, BRA.
  • Duquia RP; Dermatology Service, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, BRA.
  • Pizutti GW; Dermatology Service, Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, BRA.
  • Nunes FB; Dermatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, BRA.
  • Branchini G; Dermatology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, BRA.
  • Mosquera ESB; Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, BRA.
  • Bonamigo RR; Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, BRA.
Cureus ; 14(11): e31566, 2022 Nov.
Article em En | MEDLINE | ID: mdl-36540510
Objectives The aim of this study was to ascertain whether pattern of cutaneous lesions, age, sex, ethnicity, long-term medication use, arterial oxygen saturation at the first examination, setting of care, and number of medications used to treat SARS-CoV-2 infection are associated with mortality in patients with a confirmed diagnosis of coronavirus disease 2019 (COVID-19) and cutaneous manifestations. In addition, to evaluate the occurrence of cutaneous manifestations in patients with a confirmed diagnosis of COVID-19 through a review of medical records and in-person evaluation by a dermatologist. Methods This investigation consisted of two components - (A) a cross-sectional study with a retrospective review of the medical records of all patients with a positive reverse-transcriptase polymerase chain reaction (RT-PCR) test for SARS-CoV-2 treated at Santa Casa de Misericórdia de Porto Alegre between March 2020 and November 2020, and (B) a prospective case series with in-person skin examination by an attending dermatologist of all patients admitted to COVID-19 wards between April 2021 and July 2021. The pattern of skin lesions and other variables were assessed. Results Information from 2968 individuals with COVID-19 was collected (2826 from the medical records and 142 from the in-person examination by a dermatologist). Of these, a total of 51 patients (1.71%) had COVID-19-related cutaneous lesions - 36 from the medical records group (1.27% of cutaneous manifestations) and 15 from the examinated group (10.56% of cutaneous manifestations). Of 51 patients, 15 (29.41%) died. There was no association between mortality and patterns of cutaneous manifestations. The variables male sex (p=0.021), intensive care unit (ICU) admission (p=0.001), and use of three or more antibiotics (p=0.041) were associated with higher mortality. Conclusions The risk factors, proven by our study, for mortality in patients with COVID-19 and cutaneous manifestations were male sex, ICU stays, and use of three or more antibiotics. Using the review of medical records as a tool for evaluating cutaneous manifestations related to COVID-19, there are about 10 times fewer occurrences when compared to in-person evaluation by a dermatologist.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Cureus Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies País/Região como assunto: America do sul / Brasil Idioma: En Revista: Cureus Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos