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Detection and genetic characterization of feline retroviruses in domestic cats with different clinical signs and hematological alterations.
Acevedo-Jiménez, Gabriel Eduardo; Sarmiento-Silva, Rosa Elena; Alonso-Morales, Rogelio Alejandro; Córdova-Ponce, Rodolfo; Ramírez-Álvarez, Hugo.
Afiliação
  • Acevedo-Jiménez GE; Virology, Genetics and Molecular Biology Laboratory, Faculty of Higher Studies, Veterinary Medicine, Campus 4. National Autonomous University of Mexico, 54714, Cuautitlan Izcalli, Mexico, Mexico.
  • Sarmiento-Silva RE; Department of Microbiology and Immunology, Faculty of Veterinary Medicine and Zootechnics, National Autonomous University of Mexico, University City, 04510, Mexico City, Mexico.
  • Alonso-Morales RA; Department of Genetics and Biostatistics, Faculty of Veterinary Medicine and Zootechnics, National Autonomous University of Mexico, University City, 04510, Mexico City, Mexico.
  • Córdova-Ponce R; Virology, Genetics and Molecular Biology Laboratory, Faculty of Higher Studies, Veterinary Medicine, Campus 4. National Autonomous University of Mexico, 54714, Cuautitlan Izcalli, Mexico, Mexico.
  • Ramírez-Álvarez H; Virology, Genetics and Molecular Biology Laboratory, Faculty of Higher Studies, Veterinary Medicine, Campus 4. National Autonomous University of Mexico, 54714, Cuautitlan Izcalli, Mexico, Mexico. ramiralh@unam.mx.
Arch Virol ; 168(1): 2, 2022 Dec 19.
Article em En | MEDLINE | ID: mdl-36534205
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are globally distributed retroviruses that infect domestic cats and cause various syndromes that can lead to death. The aim of this study was to detect and genotype feline retroviruses in Mexican domestic cats. We used PCR assays to identify proviral DNA and viral RNA in 50 domestic cats with different clinical signs and hematological alterations. Endogenous FeLV (enFeLV) was identified in the genomic DNA of all cats in the study, and we detected transcripts of the LTR region of enFeLV in 48 individuals. Exogenous FeLV (exFeLV) was found in 13 cats. Furthermore, we detected FIV proviral DNA in 10 cats. The enFeLV sequences were shown to be the most variable, while the exFeLV sequences were highly conserved and related to previously reported subgroup A sequences. Sequencing of the FIV gag gene revealed the presence of subtype B in the infected cats.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Felina / Vírus da Imunodeficiência Felina Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Arch Virol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Áustria
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Felina / Vírus da Imunodeficiência Felina Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Arch Virol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: México País de publicação: Áustria