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Sewage from a secondary hospital in Ribeirão Preto, southeastern Brazil: a source of multidrug-resistant Enterobacteriaceae.
Nakamura-Silva, Rafael; de Sousa, Ricardo Coelho; Fujimoto, Rodrigo Yudi; Pitondo-Silva, André.
Afiliação
  • Nakamura-Silva R; Programa de Pós-Graduação em Tecnologia Ambiental, Universidade de Ribeirão Preto-UNAERP, Bloco J, Laboratório 1, Av. Costábile Romano, 2201, São Paulo 14096­900, Ribeirânia, Ribeirão Preto, Brazil.
  • de Sousa RC; Empresa Brasileira de Pesquisa Agropecuária-EMBRAPA, Unidade Tabuleiros Costeios, Av. Beira Mar, 3250 Jardins, Sergipe, 49025040, Aracaju, Brazil.
  • Fujimoto RY; Empresa Brasileira de Pesquisa Agropecuária-EMBRAPA, Unidade Tabuleiros Costeios, Av. Beira Mar, 3250 Jardins, Sergipe, 49025040, Aracaju, Brazil.
  • Pitondo-Silva A; Programa de Pós-Graduação em Tecnologia Ambiental, Universidade de Ribeirão Preto-UNAERP, Bloco J, Laboratório 1, Av. Costábile Romano, 2201, São Paulo 14096­900, Ribeirânia, Ribeirão Preto, Brazil. andre@pitondo.com.br.
Environ Monit Assess ; 195(1): 204, 2022 Dec 17.
Article em En | MEDLINE | ID: mdl-36527506
Antimicrobial resistance is one of the severe threats to global health. Hospital sewage can serve as a reservoir for multi-resistant bacteria and promote the spread of antimicrobial resistance. This study aimed to investigate the antimicrobial susceptibility and the pathogenic potential of Enterobacteriaceae isolated from the sewage of a secondary hospital in Ribeirão Preto, a city in southeastern Brazil. The strains were isolated by membrane filtration and identified by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF). The antimicrobial susceptibility profile was performed by disk diffusion. Polymerase chain reaction (PCR) assays were used to detect virulence genes among the strains. Twenty-eight isolates were obtained, with Klebsiella pneumoniae being the predominant species (71.4%, n = 20). All isolates were classified as multidrug-resistant, including four isolates that were non-susceptible to at least 50% of the tested antibiotics. All isolates were also non-susceptible to cefuroxime and sulfonamides antibiotics; however, they were susceptible to norfloxacin, ofloxacin, amikacin, gentamicin, netilmicin, ertapenem, cefazolin, cefaclor, and cefotetan. The virulence genes ycfM, fimH, mrkD, kfu, and entB were detected in several isolates. Our study showed that even in a secondary hospital, without the routine of major surgeries and intensive care admissions, the hospital sewage can harbor a high percentage of multidrug-resistant bacteria with pathogenic potential. This leads to the worrying risk of public health and environmental contamination.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esgotos / Enterobacteriaceae País/Região como assunto: America do sul / Brasil Idioma: En Revista: Environ Monit Assess Assunto da revista: SAUDE AMBIENTAL Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esgotos / Enterobacteriaceae País/Região como assunto: America do sul / Brasil Idioma: En Revista: Environ Monit Assess Assunto da revista: SAUDE AMBIENTAL Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda