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A Case Series of Stereotactic Biopsy of Brainstem Lesions through the Transfrontal Approach.
Escobar-Vidarte, Oscar Andrés; Griswold, Dylan Paul; Orozco-Mera, Javier; Mier-Garcia, Juan Felipe; Peralta Pizza, Fernando.
Afiliação
  • Escobar-Vidarte OA; Department of Neurosurgery, University del Valle, Cali, Valle del Cauca, Colombia.
  • Griswold DP; Department of Neurosurgery, University Hospital del Valle, Cali, Valle del Cauca, Colombia.
  • Orozco-Mera J; Department of Neurosurgery, Castellana Clinic, Cali, Valle del Cauca, Colombia.
  • Mier-Garcia JF; Department of Neurosurgery, Latin American Institute of Neurology and the Nervous System, Bogota, Colombia.
  • Peralta Pizza F; Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom.
J Neurol Surg Rep ; 83(4): e123-e128, 2022 Oct.
Article em En | MEDLINE | ID: mdl-36467870
Background and Importance Brainstem lesions may be unresectable or unapproachable. Regardless, the histopathological diagnosis is fundamental to determine the most appropriate treatment. We present our experience with transfrontal stereotactic biopsy technique for brainstem lesions as a safe and effective surgical route even when contralateral transhemispheric approach is required for preservation of eloquent tissue. Clinical Presentation Twenty-five patients underwent surgery by transfrontal approach. Medical records were reviewed for establishing the number of patients who had postoperative histopathological diagnosis and postoperative complications. Twenty-four patients (18 adults and 7 children) had histopathological diagnosis. There were 18 astrocytomas documented, of which 12 were high grade and 6 low grade. The other diagnoses included viral encephalitis, post-renal transplant lymphoproliferative disorder, nonspecific chronic inflammation, Langerhans cell histiocytosis, and two metastases. No case was hindered by cerebrospinal fluid loss or ventricular entry. Complications included a case of mesencephalic hemorrhage with upper limb monoparesis and a case of a partially compromised third cranial nerve in another patient without associated bleeding. Conclusion Stereotactic biopsy of brainstem lesions by transfrontal ipsilateral or transfrontal transhemispheric contralateral approaches is a safe and effective surgical approach in achieving a histopathological diagnosis in both pediatric and adult populations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Neurol Surg Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Neurol Surg Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Colômbia País de publicação: Alemanha