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Role of Probiotics in Patients with Allergic Rhinitis: A Systematic Review of Systematic Reviews.
Iftikhar, Haissan; Awan, Muhammad Ozair; Awan, Muhammad Sohail; Mustafa, Khawaja; Das, Jai K; Ahmed, Shahzada Khuram.
Afiliação
  • Iftikhar H; Department of Otolaryngology, Rawal Institute of Health Sciences, Islamabad, Pakistan.
  • Awan MO; Department of Surgery, Aga Khan University Medical College, Karachi, Pakistan.
  • Awan MS; Department of Surgery, Aga Khan University Medical College, Karachi, Pakistan.
  • Mustafa K; Department of Surgery, Aga Khan University Medical College, Karachi, Pakistan.
  • Das JK; Division of Women and Child Health, Aga Khan University, Karachi, Pakistan.
  • Ahmed SK; Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Int Arch Otorhinolaryngol ; 26(4): e744-e752, 2022 Oct.
Article em En | MEDLINE | ID: mdl-36405454
Introduction Allergic rhinitis (AR) is estimated to affect up to 30% of the world population. With the rise in cases, newer treatment modalities have been explored. Probiotics have shown to reduce symptoms of AR and improve quality of life. A few systematic reviews have been published aiming to assess the role of probiotics in AR. Objectives To consolidate the recent evidence with an overview of systematic reviews by extracting data regarding subjective outcomes (from quality of life questionnaires, the Total Nasal Symptom Score, the Total Ocular Symptom Score, the Daily Total Symptom Score, the incidence of AR, and the Rhinitis Total Symptom Score) and objective outcomes (levels of antigen-specific immunoglobulin E [IgE], total IgE, interleukin 10 [IL-10], interferon gamma [IFNG], eosinophil, and the T helper 1/T helper 2 [Th1/Th2] ratio). Data Synthesis We conducted a literature search on the PubMed, EBSCO CINAHL, EBSCO Dentistry & Oral Sciences Source, and Cochrane Library up to April 14, 2020. The qualitative assessment was performed using the Assessing the Methodological Quality of Systematic Reviews (AMSTAR-2) tool. A total of 419 titles were screened, and 3 systematic reviews met our eligibility criteria. Probiotics in the treatment of AR have been shown to improve quality of life, the total nasal and ocular symptom scores, the daily total symptom scores and Th1/Th2 ratio. No difference was ascertained for rhinitis total symptom score, and the rates of antigen-specific IgE, total IgE, IL-10, INFG and eosinophil. Conclusion The present review showed that there is considerable evidence that probiotics are useful in the treatment of AR. Further randomized trials targeting the limitations of the currently-available evidence can help ascertain the usefulness of probiotics in cases of AR.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Overview / Qualitative_research / Systematic_reviews Aspecto: Patient_preference Idioma: En Revista: Int Arch Otorhinolaryngol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Paquistão País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Overview / Qualitative_research / Systematic_reviews Aspecto: Patient_preference Idioma: En Revista: Int Arch Otorhinolaryngol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Paquistão País de publicação: Brasil